Alternate drugs to consider Valacyclovir References 1. Exposure of babies to C 15 -C 45 mineral paraffins from human milk and breast salves. Unexpected accumulation of acyclovir in breast milk with estimation of infant exposure. Acyclovir in human breast milk. What conditions does Acyclovir treat?
Side Effects Nausea , diarrhea , headache , or vomiting may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects.
Many people using this medication do not have serious side effects. Tell your doctor right away if any of these unlikely but serious side effects occur: This medication may rarely cause a life-threatening disorder that affects the blood cells , kidneys , and other parts of the body.
This disorder is more likely to occur if you have conditions related to a weakened immune system such as HIV disease, bone marrow transplant , kidney transplant. Seek immediate medical attention if any of these rare but serious side effects occur: A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction , including: This is not a complete list of possible side effects.
If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. The median age of persons observed through a recurrence was None of the patients reported adverse events, including allergic reactions. Acyclovir therapy mg po t.
The median duration of lesions was 4 days in the acyclovir group and 6 days in the placebo group, with a hazard ratio of 1. The median duration of all episode symptoms was 4 days in the acyclovir group and 6 days in the placebo group hazard ratio, 2.
Men differed from women with regard to the duration of lesions and the duration of all episode symptoms: Table 2 Comparison of clinical and virological outcomes among subjects who received either acyclovir mg given by mouth t. Table 3 Hazard ratios for duration of episode and lesion healing time, stratified by sex.
Table 3 View large Download slide Hazard ratios for duration of episode and lesion healing time, stratified by sex. HSV-2 was isolated from 9 participants To ascertain whether acyclovir administration for 2 days does not result in rapid reactivation of HSV infection and a shorter time to a subsequent recurrence when the therapy is discontinued, we compared the time to the second recurrence in 22 men and 37 women who were treated with the study drug for 2 consecutive recurrences.
As shown in figure 1D, there was no discernible difference between the 2 groups, with a median time of 48 days in the acyclovir group and of Two clinical studies conducted by Dr. Click here to read a more detailed description of these studies.
The three leading drugs against genital herpes are acyclovir Zovirax , famciclovir Famvir , and valacyclovir Valtrex. All drugs are used in both episodic and suppressive treatment of the disease. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
For oral dosage forms capsules, oral suspension, or tablets: For treatment of genital herpes: Adults and children 12 years of age and older— milligrams mg five times a day for ten days. Children up to 12 years of age—Use and dose must be determined by the doctor. If oral variants of Zovirax commonly cause diarrhea, nausea, headaches or pains in abdominal, parenteral ones bring forward rash and hives, phlebitis or inflammation in the injection site, pains in abdominal and vomiting, as well as raised transaminase levels.
Acyclovir is registered to have interactions with over thirty diverse medications usually moderate. Therefore, before starting the treatment, make sure your doctor or the pharmacist you buy Zovirax from are aware of all the drugs you take on a daily basis. Do never start or cease a course of treatment with Zovirax unless your doctor tells. Neither should you change the dose on your own.
Additionally, read the label of the medicine carefully to find out whether there is any ingredient you have an allergy for. This may be fraught with serious consequences. Most of all, an overdose with Zovirax may lead to problems with a kidney. Here are the main symptoms of an overdose: Zovirax tablets and capsules should be taken with a full glass of water.
During the entire course of treatment, patients are advised to use much water.
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