Benicar HCT should be stored at room temperature away from direct sunlight and heat. If you are allergic to any of the ingredients of Benicar HCT, you should avoid taking it and inform your doctor. You must consult your doctor if you are taking any other medications as they may interact with Benicar HCT, including any other blood pressure medications, steroids, lithium, cholestyramine, insulin, diabetic medications, barbiturates, other diuretics, aspiring or NSAIDs, muscle relaxers or narcotics.

It is important that you inform your doctor if you are pregnant, planning to conceive or breastfeeding as Benicar HCT may cause harm to unborn and new born babies.

Do not drink alcohol as this may increase the side effects of Benicar HCT. The generic alternative is not manufactured by the company that makes the brand product. This website contracts with dispensaries around the world that ship products directly to our customers. The items within your order may be shipped from any one of these jurisdiction depending on the availability and cost of the products at the time you place your order. The products are sourced from these countries as well as others.

Please note that the product appearance may vary from actual product received depending on availability. Generic drugs are medications that have comparable medicinal ingredients as the original brand name drug, but which are generally cheaper in price.

Nearly 1 in 3 drugs dispensed are "generic". If you also take certain drugs to lower your cholesterol bile acid-binding resins such as cholestyramine , colesevelam or colestipol , take this product at least 4 hours before or at least 4 to 6 hours after these medications.

The dosage is based on your medical condition and response to treatment. Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day. It is important to continue taking this medication even if you feel well. Most people with high blood pressure do not feel sick. Tell your doctor if your condition does not improve or if it worsens for example, your blood pressure readings increase.

What conditions does Benicar HCT treat? Side Effects Dizziness or lightheadedness may occur as your body adjusts to the medication. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor right away if you have any symptoms of dehydration or mineral loss, including: Tell your doctor right away if you have any serious side effects, including: A very serious allergic reaction to this drug is rare.

However, get medical help right away if you notice any symptoms of a serious allergic reaction , including: All patients should be cautioned that inadequate fluid intake, excessive perspiration, diarrhea or vomiting can lead to an excessive fall in blood pressure, with the same consequences of light-headedness and possible syncope.

Drug Interactions Olmesartan medoxomil No significant drug interactions were reported in studies in which olmesartan medoxomil was co-administered with hydrochlorothiazide, digoxin or warfarin in healthy volunteers.

Olmesartan medoxomil is not metabolized by the cytochrome P system and has no effects on P enzymes; thus, interactions with drugs that inhibit, induce or are metabolized by those enzymes are not expected. Hydrochlorothiazide When administered concurrently the following drugs may interact with thiazide diuretics: Alcohol, Barbiturates, Or Narcotics— potentiation of orthostatic hypotension may occur.

Antidiabetic Drugs oral agents and insulin — dosage adjustment of the antidiabetic drug may be required. Other Antihypertensive Drugs— additive effect or potentiation.

Cholestyramine and Colestipol Resins— absorption of hydrochlorothiazide is impaired in the presence of anionic exchange resins.

Single doses of either cholestyramine or colestipol resins bind the hydrochlorothiazide and reduce its absorption from the gastrointestinal tract by up to 85 and 43 percent, respectively. Corticosteroids, ACTH— intensified electrolyte depletion, particularly hypokalemia.

Norepinephrine — possible decreased response to pressor amines but not sufficient to preclude their use. Skeletal Muscle Relaxants, Non depolarizing e. Tubocurarine — possible increased responsiveness to the muscle relaxant. Lithium— should not generally be given with diuretics. Diuretic agents reduce the renal clearance of lithium and add a high risk of lithium toxicity. Refer to the package insert for lithium preparations before use of such preparation with olmesartan medoxomil-hydrochlorothiazide.

Non-steroidal Anti-inflammatory Drugs— in some patients the administration of a non-steroidal anti-inflammatory agent can reduce the diuretic, natriuretic and antihypertensive effects of loop, potassium-sparing and thiazide diuretics. Therefore, when olmesartan medoxomil-hydrochlorothiazide tablets and non-steroidal anti-inflammatory agents are used concomitantly, the patients should be observed closely to determine if the desired effect of the diuretic is obtained.

Carcinogenesis, Mutagenesis, Impairment of Fertility Olmesartan medoxomil-hydrochlorothiazide No carcinogenicity studies with olmesartan medoxomil-hydrochlorothiazide have been conducted. Its action is, therefore, independent of the pathways for angiotensin II synthesis.

An AT2 receptor is found also in many tissues, but this receptor is not known to be associated with cardiovascular homeostasis. Olmesartan has more than a 12,fold greater affinity for the AT1 receptor than for the AT2 receptor. Blockade of the angiotensin II receptor inhibits the negative regulatory feedback of angiotensin II on renin secretion, but the resulting increased plasma renin activity and circulating angiotensin II levels do not overcome the effect of olmesartan on blood pressure.

Hydrochlorothiazide Hydrochlorothiazide is a thiazide diuretic. Thiazides affect the renal tubular mechanisms of electrolyte reabsorption, directly increasing excretion of sodium and chloride in approximately equivalent amounts. Indirectly, the diuretic action of hydrochlorothiazide reduces plasma volume, with consequent increases in plasma renin activity, increases in aldosterone secretion, increases in urinary potassium loss, and decreases in serum potassium.

The renin-aldosterone link is mediated by angiotensin II, so co-administration of an angiotensin II receptor antagonist tends to reverse the potassium loss associated with these diuretics. The mechanism of the antihypertensive effect of thiazides is not fully understood. Pharmacodynamics Olmesartan medoxomil Olmesartan medoxomil doses of 2. Plasma concentrations of angiotensin I and angiotensin II and plasma renin activity PRA increase after single and repeated administration of olmesartan medoxomil to healthy subjects and hypertensive patients.

Repeated administration of up to 80 mg olmesartan medoxomil had minimal influence on aldosterone levels and no effect on serum potassium. Hydrochlorothiazide After oral administration of hydrochlorothiazide, diuresis begins within 2 hours, peaks in about 4 hours and lasts about 6 to 12 hours. Drug Interactions Alcohol, barbiturates, or narcotics: Potentiation of orthostatic hypotension may occur. Skeletal muscle relaxants, non-depolarizing e. Increased responsiveness to the muscle relaxant may occur.

Thiazide-induced hypokalemia or hypomagnesemia may predispose to digoxin toxicity. Olmesartan medoxomil is completely bioactivated by ester hydrolysis to olmesartan during absorption from the gastrointestinal tract. After oral administration, the peak plasma concentration Cmax of olmesartan is reached after 1 to 2 hours. Food does not affect the bioavailability of olmesartan. Olmesartan shows linear pharmacokinetics following single oral doses of up to mg and multiple oral doses of up to 80 mg.

Steady-state levels of olmesartan are achieved within 3 to 5 days and no accumulation in plasma occurs with once-daily dosing. Peak plasma hydrochlorothiazide concentrations Cmax are reached within 2 to 5 hours after oral administration. There is no clinically significant effect of food on the bioavailability of hydrochlorothiazide. The pharmacokinetics of hydrochlorothiazide is dose proportional in the range of The volume of distribution of olmesartan is approximately 17 L.

The protein binding is constant at plasma olmesartan concentrations well above the range achieved with recommended doses.

Benicar HCT 20-12.5 mg

Increased responsiveness to the muscle relaxant 20mg occur. All benicar and registered trademarks are the property of their respective owners. Hct must also cut down on alcohol consumption as benicar may 20mg the side effects of the medication. Buy zithromax mastercard transient hypotensive 12.5 is not a contraindication to further treatment. It can be taken with or 12.5 food. Minor differences were observed in the pharmacokinetics of olmesartan in women compared to men. Systemic Lupus Erythematosus Thiazide diuretics have been reported to cause exacerbation or activation of systemic lupus erythematosus. Some products have ingredients that could raise your blood pressure or worsen your heart failure. Monitor renal function periodically in these patients. This card carries no cash value. Alopecia, pruritus Data from one controlled trial and an epidemiologic study have suggested that high-dose olmesartan may increase cardiovascular CV risk in diabetic patients, benicar hct 20mg 12.5, but the overall data are not conclusive. If hypotension does occur, the patient should be placed in the supine position and, if necessary, benicar hct 20mg 12.5, given an intravenous infusion of normal saline. Nonclinical Toxicology Carcinogenesis, Mutagenesis, Impairment Of Fertility Olmesartan Medoxomil And Hydrochlorothiazide No carcinogenicity studies with olmesartan medoxomil and hydrochlorothiazide have been hct.

Benicar HCT to treat Hypertension

DESCRIPTION

Increases in cholesterol and triglyceride levels may be associated with thiazide diuretic therapy, benicar hct 20mg 12.5. Offer not valid with any other program, discount or incentive. Benicar HCT works by keeping the blood vessels from narrowing, hct that blood pressure is 20mg at a lower level, benicar hct 20mg 12.5. Hydrochlorothiazide is slightly soluble in water but freely soluble in sodium hydroxide 12.5. The pharmacokinetics of hydrochlorothiazide is dose proportional in the range of Thiazides cross the placental 12.5 and appear in cord blood. Consult your doctor before breast-feeding. It was also not genotoxic in vivo in assays hct mouse germinal cell chromosomes, Benicar hamster bone marrow chromosomes, or the Drosophila 20mg recessive lethal trait gene. Tell your doctor if your condition does not benicar or if it worsens for example, your blood pressure readings increase. No studies of impairment of fertility with olmesartan medoxomil-hydrochlorothiazide have been conducted.

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