In another study, children 7 to 16 years of age with cancer who underwent scheduled, periodic, stressful events such as bone marrow aspirations and spinal taps, alprazolam was shown to be safe and useful for these types of procedures [Pfefferbaum ]. Additional data may be necessary to further define the role of alprazolam when treating children with this condition.
Contraindications Hypersensitivity to alprazolam or any component of the formulation cross-sensitivity with other benzodiazepines may exist ; acute narrow-angle glaucoma; concurrent use with ketoconazole, itraconazole, or other potent CYP3A4 inhibitors.
Additional contraindications not in US labeling: Myasthenia gravis; severe hepatic insufficiency; severe respiratory insufficiency; sleep apnea. Titrate dose gradually as needed and tolerated. Periodic reassessment and consideration of dosage reduction is recommended.
Immediate release tablet, oral concentrate, orally-disintegrating tablet: Switching from immediate release to extended release: Patients may be switched to extended release tablets by taking the total daily dose of the immediate release tablets and giving it once daily using the extended release preparation. Preoperative anxiety off-label use: Abrupt discontinuation should be avoided. Daily dose may be decreased by 0. If withdrawal symptoms occur, resume previous dose and discontinue on a less rapid schedule.
Titrate gradually, if needed and tolerated. Refer to adult dosing. Pediatric Anxiety off-label use: See "Dose Reduction" comment in adult dosing. Renal Impairment There are no dosage adjustments provided in the manufacturer's labeling; use caution. Hepatic Impairment Immediate release tablet, oral concentrate, orally-disintegrating tablet: Crush sixty 2 mg tablets in a mortar and reduce to a fine powder.
Add 40 mL of vehicle and mix to a uniform paste; mix while adding the vehicle in incremental proportions to almost mL; transfer to a calibrated bottle, rinse mortar with vehicle, and add a quantity of vehicle sufficient to make mL. Label "shake well" and "refrigerate". Stable for 60 days. Harvey Whitney Books Co, Administration Immediate release preparations: Can be administered sublingually if oral administration is not possible; absorption and onset of effect are comparable to oral administration Scavone ; Scavone Extended release tablet: Should be taken once daily in the morning; do not crush, break, or chew.
Use only the provided calibrated dropper to withdraw the prescribed dose. The prepared mixture should be administered immediately. Using dry hands, place tablet on top of tongue and allow to disintegrate. Administration with water is not necessary. Dietary Considerations Orally-disintegrating tablets may contain phenylalanine. Storage Immediate release tablets: Discard opened bottle after 90 days. Drug Interactions Alcohol Ethyl: Monitor for increased aripiprazole pharmacologic effects.
Consult full interaction monograph for specific recommendations. Monitor therapy Azelastine Nasal: Consider therapy modification Boceprevir: In patients receiving boceprevir, consider lower alprazolam doses and monitor closely for symptoms of toxicity including prolonged sedation and respiratory depression. Consider therapy modification Bosentan: Monitor therapy Brimonidine Topical: Consider therapy modification Cannabis: Use of ceritinib with a narrow therapeutic index CYP3A substrate eg, alfentanil, cyclosporine, dihydroergotamine, ergotamine, fentanyl, pimozide, quinidine, sirolimus, tacrolimus should be avoided when possible.
Monitor closely for evidence of excessive CNS depression. The chlormethiazole labeling states that an appropriately reduced dose should be used if such a combination must be used. Consider therapy modification Chlorphenesin Carbamate: Consider decreasing the dose of or possibly discontinuing benzodiazepines prior to initiating clozapine.
Consider therapy modification CNS Depressants: Consider an alternative for one of the interacting drugs. Some combinations may be specifically contraindicated. Consult appropriate manufacturer labeling. Consider using an alternative agent that is less likely to interact.
Consider therapy modification Dabrafenib: Seek alternatives to the CYP3A4 substrate when possible. If concomitant therapy cannot be avoided, monitor clinical effects of the substrate closely particularly therapeutic effects. Consider therapy modification Deferasirox: Monitor therapy Dimethindene Topical: Consider dose reductions of droperidol or of other CNS agents e.
Consider therapy modification Enzalutamide: Concurrent use of enzalutamide with CYP3A4 substrates that have a narrow therapeutic index should be avoided. Use of enzalutamide and any other CYP3A4 substrate should be performed with caution and close monitoring. Consider therapy modification Erythromycin Systemic: Monitor therapy Fusidic Acid Systemic: Avoid concomitant use of hydrocodone and benzodiazepines or other CNS depressants when possible.
These agents should only be combined if alternative treatment options are inadequate. If combined, limit the dosages and duration of each drug. Consider therapy modification HydrOXYzine: Avoid combination Kava Kava: Monitor therapy Ketoconazole Systemic: Consider therapy modification Magnesium Sulfate: May enhance the sedative effect of Benzodiazepines. Alcohol interaction Alprazolam can cause drowsiness, dizziness, or lightheadedness.
The use of drinks that contain alcohol raises your risk of these side effects. Try to avoid drinking alcohol while you take this drug. Warnings for people with certain health conditions For people with depression: If you have pre-existing depression, this drug may make your condition worse.
If your depression gets worse or you have suicidal thoughts, call your doctor right away. For people with acute narrow-angle glaucoma: This drug can make your condition worse. Do not take this drug if you have acute narrow-angle glaucoma. For people with a history of alcoholism, drug abuse, or personality disorder: This drug can lead to physical and psychological dependence addiction. If you have a history of these conditions, you have a greater risk of dependence on this drug.
For people with liver disease: It may be harder for your body to break down this drug. This can increase the amount of the drug in your body, which can lead to more side effects.
For people with obesity: For people with severe lung disease: Talk with your doctor about whether this drug is safe for you.
Warnings for other groups For pregnant women: This drug is a category D pregnancy drug. That means two things: Research in humans has shown adverse effects to the fetus when the mother takes the drug.
This drug should only be used during pregnancy in serious cases where it's needed to treat a dangerous condition in the mother. Ask your doctor to tell you about the specific harm that may be done to the fetus. For women who are breastfeeding: This drug may pass into breast milk and may cause side effects in a child who is breastfed.
Tags: pletal medication generic kamagra soft tabs 100mg how to shoot up oxycodone 5mg
© Copyright 2017 Alprazolam 1 mg tablet sta. morbidevoci.ch.