In animal studies, it caused low birth weight and birth defects. However, it is not known whether these effects would occur in humans. Tell your doctor if you are pregnant or if you become pregnant while using this medicine. It is not known whether baclofen passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are using this medicine. Using baclofen may increase your risk of developing an ovarian cyst.
Talk with your doctor about your specific risk. Baclofen is not approved for use by anyone younger than 12 years old. How should I take baclofen? Take baclofen exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results.
Do not use this medicine in larger or smaller amounts or for longer than recommended. Take 15 mg three times per day. Days 10 through Take 20 mg three times per day. Your doctor will slowly increase your dosage every three days. Your doctor may further increase your dosage if needed. A total of 80 mg per day taken in four divided doses of 20 mg each.
Child dosage ages 12 to 17 years Typical starting dosage: Days 7 through 9: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. This information is not a substitute for medical advice. Always speak with your doctor or pharmacist about dosages that are right for you. Take as directed Baclofen oral tablet is used for either short-term or long-term treatment.
Your medication may not work as well or may stop working completely. For this drug to work well, a certain amount needs to be in your body at all times. If you take too much: You could have dangerous levels of the drug in your body. Symptoms of an overdose of this drug include: If your symptoms are severe, call or go to the nearest emergency room right away. Dispense in a well-closed container as defined in the USP. Use child-resistant closure as required. Rare instances of dyspnea , palpitation, chest pain, syncope.
Instances of rash, pruritus , ankle edema, excessive perspiration , weight gain, nasal congestion. Some of the CNS and genitourinary symptoms may be related to the underlying disease rather than to drug therapy.
The following laboratory tests have been found to be abnormal in a few patients receiving baclofen: Hallucinations and seizures have occurred on abrupt withdrawal of baclofen. Therefore, except for serious adverse reactions, the dose should be reduced slowly when the drug is discontinued. Because baclofen is primarily excreted unchanged through the kidneys, it should be given with caution, and it may be necessary to reduce the dosage.
Baclofen has not significantly benefited patients with stroke. These patients have also shown poor tolerability to the drug. Baclofen has been shown to increase the incidence of omphaloceles ventral hernias in fetuses of rats given approximately 13 times the maximum dose recommended for human use, at a dose which caused significant reductions in food intake and weight gain in dams.
This abnormality was not seen in mice or rabbits. There was also an increased incidence of incomplete sternebral ossification in fetuses of rats given approximately 13 times the maximum recommended human dose, and an increased incidence of unossified phalangeal nuclei of forelimbs and hindlimbs in fetuses of rabbits given approximately 7 times the maximum recommended human dose.
In mice, no teratogenic effects were observed, although reductions in mean fetal weight with consequent delays in skeletal ossification were present when dams were given 17 and 34 times the human daily dose.
Hallucinations and seizures have occurred on abrupt withdrawal of Baclofen, baclofen 10 mg half life. However, this article should not be used as a substitute for the knowledge and expertise of a half healthcare half. To make sure this medicine is safe for you, tell your doctor if you have: This is particularly relevant if the patients is ambulant in order to minimise muscle weakness in the unaffected limbs or where spasticity is necessary for support. Occasionally or rarely, dysuria, frequency of micturition and enuresis are reported frequently. However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. Treatment In the alert patient, empty baclofen stomach promptly by induced emesis followed by lavage. Do not drive, use machinery, or do any activity that requires alertness until you are life you can perform such activities safely. The clinical relevance of these findings is not known. It is not known whether this drug baclofen excreted in life milk, baclofen 10 mg half life.
Pharmacological properties Pharmacotherapeutic group: Do not take extra medicine to make up the missed dose. These patients have also shown poor tolerability to the drug. Baclofen is used to treat muscle symptoms caused by multiple sclerosisincluding spasm, baclofen, and stiffness. The benefits of the treatment for the mother must be carefully weighed against the possible risks for the child. The usual daily dosage for maintenance therapy ranges between 0, baclofen 10 mg half life. Are there any alternatives? Because Baclofen is primarily excreted half through the kidneys, it should be given with caution, and it may be necessary to reduce the dosage. Should nausea persist following a reduction in dosage, it is recommended that Baclofen be ingested with food or a milk drink. Keep these considerations in mind if your doctor prescribes baclofen life tablet for you. Take baclofen exactly as prescribed by your doctor.
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