In addition to children using these substances being shorter, they are also usually lighter — weighing less than non-medicated counterparts. Withdrawal Those taking Concerta and Adderall over a long-term may struggle with discontinuation.
Discontinuation is thought to be most severe among those who used these medications for a long-term e. Since Adderall is considered the more potent of the two drugs, the highest daily dose of Adderall will likely present more discontinuation difficulties than the highest daily dose of Concerta. There are many anecdotal reports that highlight the severity of both Concerta withdrawal and Adderall withdrawal. Upon discontinuation, users generally experience a variety of symptoms including: Furthermore, symptoms of ADHD may become more severe than they were prior to taking either of these drugs.
This is due to the fact that the brain becomes dependent upon the drug for everyday functioning. In some cases withdrawal can last months or years depending on how long a person had been taking either drug.
Concerta doses jump by 9 mg or 18 mg — possibly making reduction adjustments more difficult. Adderall Below is a synopsis of similarities shared between Concerta and Adderall. Each of these drugs has significant potential for abuse and dependence.
They are habit-forming and can result in psychological euphoria when ingested at high doses. They are prescribed as first-line treatments due to favorable side effect profiles and sustained efficacy. Concerta is known to elicit an effect for approximately 12 hours. Both drugs are thought to be relatively similar in terms of efficacy. However, Adderall is thought to be the more potent of the two drugs due to the fact that 10 mg of Adderall XR is equivalent to 36 mg of Concerta.
Both substances are available in generic formulations. If you have any questions regarding interactions, talk to a medical professional or pharmacist. These medications are considered legal in the United States when attained via prescription from a licensed medical professional. Without a prescription, they are considered illegal to possess.
All prescriptions for Concerta and Adderall are non-refillable. Both drugs inhibit the reuptake of neurotransmitters like dopamine and norepinephrine. This leads to increases in extracellular levels, which promotes increased attention and reductions in hyperactivity.
These drugs carry very similar side effect profiles. General side effects tend to consist of: Discontinuation from either medication is thought to be difficult. Various discontinuation symptoms include: It does this by binding to both the dopamine and norepinephrine transporters to disrupt the clearance of the two neurotransmitters from the spaces between the neurons.
However, methylphenidate is more active in binding with the dopamine transporter than with the norepinephrine transporter. Yet another way in which methylphenidate has a slightly different activity when compared to the amphetamine is in its second mechanism of action. Methylphenidate contained in Concerta also stimulates the release of more dopamine and norepinephrine into the synaptic spaces.
However, it does this to a lesser extent than the amphetamines. Moreover, the exact mechanism of releasing these neurotransmitters is still unclear but is definitely not the same as with the amphetamines.
In addition, while the amphetamines substitute for dopamine and norepinephrine at the transporters in the synapses, methylphenidate binds with the transporters. This means that the transporters are still working in the case of Adderall but they are removing amphetamines instead. With Concerta, the transporters are blocked from functioning at all.
The overall effect of methylphenidate is to improve the symptoms of ADHD by reducing fatigue, improving alertness and attention while maintaining mental focus. Studies and Research The efficacy of both these stimulants has been demonstrated in classroom settings. Both the medicines have the effect of calming the user and allowing him to improve his mental concentration.
However, the long-term effects of both medications are controversial. According to Terrance Woodworth of the U. It has been shown that amphetamines are more potent than Concerta. Both medications stimulate the central nervous system. Adderall tends to have harsher side effects than Concerta. Be sure to take this drug exactly as your doctor tells you. If you have questions or concerns, talk with your doctor.
Dosage Concerta is only available as an extended-release tablet. Adderall is available as an immediate-release and extended-release drug. In the immediate-release form, the tablet releases the drug into your system right away. In the extended-release form, the capsule slowly releases small amounts of medication into your body throughout the day. If your doctor prescribes Adderall, they may start you on the immediate-release form at first.
Eventually, they may change you to the extended-release form. If, after weighing up risks versus benefits, medications are deemed appropriate to use in children with ADHD, continuous monitoring for improvement or development of side effects should be undertaken. If one ADHD medication fails, it is appropriate to try another before giving up on stimulant treatment. Stimulants are effective for ADHD; however, it is worthwhile noting that the majority of trials have been of poor quality and relatively short duration.
It is difficult for trials involving CNS stimulants not to be bias in some way — disguising the effects of a stimulant drug is practically impossible, particularly in trials comparing it to placebo, and most trial participants, clinicians and researchers are able to work out who is taking active drug and who is taking placebo.
A Cochrane group recently reviewed the results of trials involving methylphenidate for the treatment of ADHD. The only definite conclusions to come out of the review were that methylphenidate is associated with sleep problems and a decreased appetite, but trials were of too short a duration less than 6 months to confirm any risk of serious adverse effects associated with long-term use.
In another review, the Cochrane group investigated the effectiveness of amphetamines in ADHD, and 23 relevant trials were identified. Children taking amphetamine salts were also more likely to experience sleep problems, decreased appetite, and stomach pain. Although this review included a number of different types of amphetamines lisdexamfetamine, dextroamphetamine, and mixed amphetamine salts there was no evidence that one kind of amphetamine was any better than another.
These drugs also carry the risk of addiction. This is due to the fact concerta the brain becomes dependent upon the drug for everyday functioning. One person may find that Concerta works better or has more favorable side effects than Adderall and vice-versa, concerta compared adderall xr. Studies and Research The efficacy of both these stimulants has been compared in classroom settings. In regards to off-label or investigational uses, they are thought to differ. This means you can get addicted concerta this drug. Those evaluating Concerta and Adderall as potential options for the treatment of ADHD or narcolepsy all compare to know which one is more effective. Common side effects of Concerta and Adderall include: Adderall the adderall methylphenidate in the compare of Concerta has not concerta specifically investigated for all of the aforementioned conditions, it should be thought to elicit similar effects or adderall more sustained effects compared to other methylphenidate formulations, concerta compared adderall xr. Thinking or learning ability does not appear enhanced in those without ADHD.
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