Store at room temperature away from moisture, heat, and light. Dosage Information in more detail What happens if I miss a dose? Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose.
Do not take extra medicine to make up the missed dose. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at An overdose of trazodone can be fatal when it is taken with alcohol, barbiturates such as phenobarbital, or sedatives such as diazepam Valium.
Overdose symptoms may include extreme drowsiness, vomiting, penis erection that is painful or prolonged, fast or pounding heartbeat, seizure black-out or convulsions , or breathing that slows or stops. What should I avoid while taking trazodone? Do not drink alcohol. Trazodone can increase the effects of alcohol, which could be dangerous. Trazodone and alcohol in more detail Avoid getting up too fast from a sitting or lying position, or you may feel dizzy.
Get up slowly and steady yourself to prevent a fall. Trazodone may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
Ask your doctor before taking a nonsteroidal anti-inflammatory drug NSAID for pain, arthritis, fever, or swelling. This includes aspirin, ibuprofen Advil, Motrin , naproxen Aleve , celecoxib Celebrex , diclofenac, indomethacin, meloxicam, and others.
Trazodone side effects Stop taking trazodone and call your doctor at once if you have a penis erection that is painful or lasts 6 hours or longer. This is a medical emergency and could lead to a serious condition that must be corrected with surgery. Get emergency medical help if you have any signs of an allergic reaction to trazodone: Report any new or worsening symptoms to your doctor, such as: Call your doctor at once if you have: Common trazodone side effects may include: QT prolongation is a serious life-threatening condition that can cause fainting, seizures, and sudden death.
If you are at risk for heart rhythm problems e. Trazodone may cause low blood pressure and possibly cause a feeling of lightheadedness when moving from a sitting or lying position to a standing position. Trazodone can cause severe dizziness, especially when rising from a sitting or lying position. People taking medications that can cause dizziness should rise slowly from sitting or lying down to reduce the possibility of severe dizziness or fainting.
Trazodone may impair the mental or physical abilities required for potentially hazardous tasks, such as driving or operating machinery. Avoid driving, operating machinery, or performing other hazardous tasks until you have determined how this medication affects you.
Trazodone has been associated with prolonged or inappropriate erections priapism for a number of men taking this medication. If this occurs, stop taking the medication immediately and contact your doctor.
Seizures have been reported for a small number of people taking trazodone. Most of these people were already taking medications for a previously diagnosed seizure disorder. If you have a history of seizures, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed. Rarely, severe, life-threatening reactions are possible when trazodone is combined with other medications that act on serotonin, such as tricyclic antidepressants and serotonin reuptake inhibitors, which are other medications used to treat depression.
This is called serotonin syndrome. These combinations should be avoided. Symptoms of a reaction may include muscle rigidity and spasms, difficulty moving, changes in mental state including delirium and agitation. Coma and death are possible. If this medication needs to be stopped, it should be done gradually, under the supervision of your doctor. Suddenly stopping trazodone can cause anxiety, agitation or sleep problems.
The safety of trazodone for use during pregnancy has not been established. It should not be used by women who may become pregnant unless, in the opinion of their doctor, the expected benefits outweigh the potential risks.
If you are or may be pregnant, talk to your doctor about the risks and benefits of this medication.
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