Cipro 500 mg tablet dosage - Cipro (Ciprofloxacin): Side Effects, Interactions, Warning, Dosage & Uses
Drugs known to prolong QT interval Ciprofloxacin, cipro 500 mg tablet dosage, like other fluoroquinolones, should be used with caution in patients receiving drugs known to prolong the QT interval e. Class IA and III anti-arrhythmics, tricyclic antidepressants, macrolides, antipsychotics see section 4.
Chelation complex formation The simultaneous administration of ciprofloxacin oral and multivalent cation-containing drugs and mineral supplements e. Consequently, ciprofloxacin should be administered either hours before or at least 4 hours after these preparations. The restriction does not apply to antacids belonging to the class of H2 receptor blockers, cipro 500 mg tablet dosage.
Food and Dairy products: Dietary calcium as part of a meal does not significantly affect absorption, cipro 500 mg tablet dosage.
However, the concurrent administration of dairy products or mineral-fortified drinks alone e. Probenecid Probenecid interferes with renal secretion of ciprofloxacin.
Co-administration of probenecid and ciprofloxacin increases ciprofloxacin serum concentrations, cipro 500 mg tablet dosage. Metoclopramide Metoclopramide accelerates the absorption of ciprofloxacin oral resulting in a shorter time to reach maximum plasma concentrations.
No effect was seen on the bioavailability of ciprofloxacin. Omeprazole Concomitant administration of ciprofloxacin and omeprazole containing medicinal products results in a slight reduction of Cmax and AUC of ciprofloxacin. Effects of ciprofloxacin on other medicinal products: Tizanidine Tizanidine must not be administered together with ciprofloxacin see section 4.
In a clinical study with healthy subjects, there was an increase cipro serum tizanidine concentration Cmax increase: Increased serum tizanidine concentration is associated with 500 potentiated hypotensive and sedative effect. Agomelatine In clinical studies, it was demonstrated that fluvoxamine, as a strong inhibitor of the CYP 1A2 isoenzyme, markedly inhibits the metabolism of agomelatine resulting in a fold increase of agomelatine exposure. Although no clinical data are available for a possible interaction with ciprofloxacin, a dosage inhibitor of CYP 1A2, similar effects can be expected upon concomitant administration 'Cytochrome P' in section 'Special warnings and precautions for use, cipro 500 mg tablet dosage.
Zolpidem Co-administration ciprofloxacin may tablet blood levels of zolpidem, concurrent use is not recommended.
Ciprofloxacin tablets
Methotrexate Renal tubular transport of methotrexate may be inhibited by tablet administration of ciprofloxacin, potentially leading to increased plasma cipro of methotrexate and increased risk of methotrexate-associated toxic reactions. The concomitant use is not recommended see section 4. Theophylline Concurrent administration of ciprofloxacin and theophylline can cause an undesirable increase in serum theophylline concentration.
This can 500 to theophylline induced side effects that may rarely be life threatening or fatal. During the combination, serum theophylline concentrations should be checked and the theophylline dose reduced as necessary see section 4, cipro 500 mg tablet dosage.
Other xanthine derivatives On dosage administration of ciprofloxacin and caffeine or pentoxifylline oxpentifyllinecipro 500 mg tablet dosage, raised serum concentrations of these xanthine derivatives were reported. Phenytoin Simultaneous administration of ciprofloxacin and phenytoin may result in increased or reduced serum levels of phenytoin such that tablet of drug levels is recommended. 500 A dosage rise in the concentration of serum creatinine was observed when ciprofloxacin and cyclosporin containing medicinal products were administered simultaneously.
cipro
Therefore, it is frequently twice a week necessary to control the serum creatinine concentrations in these patients. Vitamin K antagonists Simultaneous administration of ciprofloxacin with a vitamin K antagonist may augment its anti-coagulant effects.
The dosage may vary with the underlying infection, age and general status of the patient so that the contribution of ciprofloxacin to the increase in INR international normalised ratio is difficult to assess.
The INR should be 500 frequently during and shortly after co-administration of ciprofloxacin with a vitamin K antagonist e. Duloxetine In clinical studies, it was demonstrated that concomitant use of duloxetine with strong inhibitors of the CYP 1A2 isozyme such as fluvoxamine, may result in an increase of AUC and Cmax of duloxetine. Cipro no clinical tablets are available on a possible interaction with ciprofloxacin, similar effects can be 500 upon concomitant administration see section 4.
Monitoring of ropinirole-related side effects and dose adjustment cipro appropriate is recommended during and shortly after co- tablet with ciprofloxacin see section 4. Although lidocaine treatment was well tolerated, a possible interaction with ciprofloxacin associated with side effects may occur upon concomitant administration, cipro 500 mg tablet dosage. Clinical surveillance and appropriate adjustment of clozapine dosage during and shortly after co-administration dosage ciprofloxacin are advised see section 4.
Ciprofloxacin Hcl
Sildenafil Cmax and AUC of sildenafil were increased approximately twofold in healthy subjects after an oral dose of 50 mg given concomitantly with mg ciprofloxacin. Therefore, caution should be used prescribing ciprofloxacin concomitantly with sildenafil taking into consideration the risks and the benefits. Check your blood sugar regularly as directed and share the results with your doctor.
Ciprofloxacin may increase the blood -sugar-lowering effects of the medication glyburide. It is cipro good habit to carry glucose tablets or gel to treat low blood sugar. 500 you don't have these reliable forms of glucose, cipro 500 mg tablet dosage, rapidly raise your blood sugar by eating a quick source of sugar such as table sugar, honey, or candy, or by dosage fruit juice or non- diet tablet.
Tell your doctor right away about the reaction and the use of this dosage. To help prevent low dosage sugareat meals on a regular schedule, and do not skip meals. Your doctor may need to switch you to another antibiotic or adjust your diabetes medications if any reaction occurs, cipro 500 mg tablet dosage. This drug may make you dizzy. Alcohol or tablet can make 500 more dizzy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely.
Cases of torsade de pointes have been reported during postmarketing surveillance in patients receiving fluoroquinolones, including CIPRO.
Avoid CIPRO in cipro tablet known prolongation of the QT interval, risk factors for QT prolongation or torsade de pointes for example, congenital long QT syndrome, uncorrected electrolyte imbalance, such as hypokalemia or hypomagnesemia and cardiac disease, such as cipro failure, myocardial infarction, or bradycardiacipro 500 mg tablet dosage, and patients receiving Class IA antiarrhythmic agents quinidine, procainamideor Class III antiarrhythmic agents amiodarone, sotaloltricyclic antidepressants, macrolides, 500 antipsychotics.
Elderly patients may also be more susceptible to drug-associated effects on the QT interval [see Adverse Reactions 6. Histopathological examination of the weight-bearing joints of these dogs revealed permanent lesions of the cartilage.
Related quinolone-class drugs also produce erosions of cartilage of weight-bearing joints and other signs of arthropathy in immature animals of various species 500 Use in Specific Populations 8, cipro 500 mg tablet dosage. Therefore, avoid excessive tablet to these sources of light. Co-administration of CIPRO and other drugs primarily metabolized by CYP1A2 for example, theophylline, methylxanthines, caffeine, tizanidine, ropinirole, clozapine, cipro 500 mg tablet dosage, olanzapine and zolpidem results in increased plasma concentrations of the co-administered drug and buying keflex online lead cipro clinically significant pharmacodynamic adverse reactions of the co-administered drug [see Drug Interactions 7 and Clinical Pharmacology Antimicrobial agents used in high dose for short periods of time to treat gonorrhea may mask or delay the symptoms of incubating syphilis.
Perform a serologic test for dosage in all patients with gonorrhea at the time of diagnosis.