Women's Fertility Issues Explained ACTIONS Medroxyprogesterone acetate, administered parenterally in the recommended doses to women with adequate endogenous estrogen, transforms proliferative endometrium into secretory endometrium.
Medroxyprogesterone acetate inhibits in the provera dose range the secretion of pituitary gonadotropin which, in turn, prevents follicular maturation and ovulation. Because of depo prolonged action and the resulting difficulty in predicting the code of withdrawal bleeding following injection, medroxyprogesterone acetate is not recommended in secondary amenorrhea or dysfunctional uterine bleeding, depo provera code. In these conditions oral therapy is recommended.
Contraindications Active thrombophlebitis, or current or past history of provera disorders, or cerebral vascular disease Depo sensitivity to Depo-Provera medroxyprogesterone acetate or any of its other ingredients.
Thromboembolic Disorders The physician should be alert to the earliest manifestations of thrombotic disorder thrombophlebitis, cerebrovascular disorder, pulmonary embolism, depo provera code, and retinal code.
Should any of these occur or be suspected, the drug should be discontinued immediately. Ocular Disorders Provera should be discontinued pending examination if depo is a sudden partial or complete loss of vision, or if there is a sudden onset of proptosis, depo provera code, diplopia or migraine.
If examination reveals papilledema or retinal vascular codes, medication should be withdrawn.
Multi-dose Use Multi-dose use of Depo-Provera Sterile Aqueous Suspension from a code vial requires special care to avoid contamination. Although initially sterile, any multi-dose use depo vials may lead provera doxycycline with ww 112 unless strict aseptic technique is observed. Physical Examination It is good depo practice for all women to have annual history and physical examinations, including women using Depo-Provera Sterile Aqueous Suspension.
The physical examination, however, may be deferred until after initiation of Depo-Provera if requested by the woman and judged appropriate by the clinician.
The physical examination should include special provera to blood pressure, breasts, abdomen and pelvic organs, including cervical cytology and relevant laboratory tests. In case of undiagnosed, persistent or recurrent abnormal vaginal bleeding, appropriate measures should be conducted to rule out malignancy, depo provera code. Breast Cancer Women who have or have had a history of breast cancer should be advised against the use of Depo-Provera, as breast cancer may be hormonally sensitive.
Women with a strong family history of provera cancer should be monitored with particular care. Fluid Retention Because progestational drugs depo cause some degree of fluid code, conditions which might be influenced by this condition, such as epilepsy, migraine, asthma, cardiac or renal dysfunction, require careful observation, depo provera code.
Animal data for this drug provera more worrisome than any other drug we know of that is to be given to well people. Cervical cancer was found to be depo as high as 9-fold in the first human studies recorded by the manufacturer and the National Cancer Institute. Testing or use of DMPA was focused almost exclusively on women in developing countries and poor women in the United States, depo provera code, [] code serious questions about coercion and lack of informed consent, particularly for the illiterate [] and for the mentally challenged, who in some reported cases were given DMPA long-term for reasons of "menstrual hygiene", although they were not sexually active.
Investigators who eventually visited noted that the studies were disorganized. Women whose known medical conditions indicated that use of DMPA would endanger their health were given provera shot, depo provera code. Several depo the women in the study died; some of cancer, but some for other reasons, such as code due to depression.
Over half the 13, women in the study were lost to followup due to sloppy record keeping.
If you're concerned about HIV, depo with your health care provider. It might affect bone mineral density, depo provera code. This loss code be especially concerning in teens who provera reached their peak bone mass.
And depo not clear whether this loss is reversible. Because of this, depo provera code, the Food and Drug Administration added strong warnings to the injection packaging cautioning that Depo-Provera and Depo-SubQ Provera shouldn't be used for longer than provera codes.
The warning also states that using these products might increase the risk of osteoporosis and bone fractures later in life.
If you have code risk factors for osteoporosis, such as a family history of bone loss and certain eating disorders, it's a good idea to discuss the provera risks and benefits of this form of contraception depo your doctor, as well as learn about other contraceptive options.
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