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Use of phenytoin for wound phenytoin
Hospital Pharmacy ; Role of phenytoin in wound healing-a wound pharmacology perspective, phenytoin decubitus ulcers. Biochem Pharmacol ; Phenytoin in decubitus ulcer. Ann Pharmacol ; Study characteristics In September we searched for randomised controlled trials RCTs that compared topical phenytoin against other treatments for treating pressure ulcers, phenytoin decubitus ulcers.
We found three small RCTs that included a total of people with pressure ulcers. The average age of participants phenytoin two studies was 45 years and 75 years in one study.
The trials compared topical phenytoin with three other treatments for pressure ulcers: The results of one study suggested that hydrocolloid dressings may slightly improve ulcer healing compared to topical phenytoin, phenytoin decubitus ulcers. However, we are uncertain whether topical phenytoin improves ulcer healing compared to simple dressings. The study which compared topical phenytoin with triple antibiotic ointment did not report any outcomes of interest to this review.
Quality of the evidence It is uncertain whether topical phenytoin improves ulcer healing for patients with grade I and II pressure ulcers.
No adverse events were reported from three small trials and minimal pain was reported in one trial. The trials did not report on some other measurements that we were phenytoin in, such as ulcer of treatment and quality decubitus life.
Two RCTs had a high risk of bias overall, phenytoin decubitus ulcers, which might have affected the results, and another RCT did not report sufficient details about how it was conducted. Further rigorous, adequately powered RCTs are needed to find whether topical phenytoin is a helpful ulcer for treating pressure ulcers.
This plain language summary is up to date as of September This review has considered the available evidence and the decubitus shows that it is uncertain whether topical phenytoin improves ulcer healing for decubituses with grade Phenytoin and II pressure ulcers.
Therefore, further rigorous, adequately powered RCTs examining the effects of topical phenytoin for treating pressure ulcers, and to report on adverse events, quality of life and costs are necessary. Phenytoin the full ulcer The results of one study suggested that hydrocolloid dressings may slightly improve ulcer healing compared to topical phenytoin, phenytoin decubitus ulcers.
However, we are uncertain whether topical phenytoin improves ulcer healing compared to simple dressings.
The study which compared decubitus phenytoin with triple antibiotic ointment did not report any outcomes of interest to this review. Quality of the evidence It is uncertain whether topical phenytoin improves ulcer healing for patients with grade I and II pressure ulcers.
No adverse events phenytoin reported from three small trials and minimal pain was reported in one trial. The trials did not report on some other measurements that we were interested in, such as cost of treatment and quality of life, phenytoin decubitus ulcers.
Two RCTs had a high risk of bias overall, which might ulcers affected the results, and another RCT did not report sufficient details about how it was conducted.
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