As these syndromes may result in potentially life-threatening conditions, treatment with fluoxetine should be discontinued if such events characterized by clusters of symptoms such as hyperthermia, rigidity, myoclonus, autonomic instability with possible rapid fluctuations of vital signs, mental status changes including confusion, irritability, extreme agitation progressing to delirium and coma occur and supportive symptomatic treatment should be initiated.
As with all antidepressants, fluoxetine should be discontinued in any patient entering a manic phase. Haemorrhage There have been reports of cutaneous bleeding abnormalities such as ecchymosis and purpura with SSRI's. Ecchymosis has been reported as an infrequent event during treatment with fluoxetine.
Other haemorrhagic manifestations e. Caution is advised in patients taking SSRI's, particularly in concomitant use with oral anticoagulants, drugs known to affect platelet function e. Seizures Seizures are a potential risk with antidepressant drugs. Therefore, as with other antidepressants, fluoxetine should be introduced cautiously in patients who have a history of seizures.
Treatment should be discontinued in any patient who develops seizures or where there is an increase in seizure frequency. Electroconvulsive Therapy ECT There have been rare reports of prolonged seizures in patients on fluoxetine receiving ECT treatment, therefore caution is advisable.
Tamoxifen Fluoxetine, a potent inhibitor of CYP2D6, may lead to reduced concentrations of endoxifen, one of the most important active metabolites of tamoxifen. Therefore, fluoxetine should whenever possible be avoided during tamoxifen treatment see section 4. This is most likely to occur within the first few weeks of treatment. In patients who develop these symptoms, increasing the dose may be detrimental. Hypoglycaemia has occurred during therapy with fluoxetine and hyperglycaemia has developed following discontinuation.
A lower dose, e. Rash and allergic reactions Rash, anaphylactoid events and progressive systemic events, sometimes serious involving skin, kidney, liver or lung have been reported. Upon the appearance of rash or of other allergic phenomena for which an alternative aetiology cannot be identified, fluoxetine should be discontinued. Weight loss Weight loss may occur in patients taking fluoxetine, but it is usually proportional to baseline body weight.
Withdrawal symptoms seen on discontinuation of SSRI treatment Withdrawal symptoms when treatment is discontinued are common, particularly if discontinuation is abrupt see section 4. The risk of withdrawal symptoms may be dependent on several factors, including the duration and dose of therapy and the rate of dose reduction. Generally, these symptoms are mild to moderate; however, in some patients they may be severe in intensity.
They usually occur within the first few days of discontinuing treatment. Generally, these symptoms are self-limiting and usually resolve within 2 weeks, though in some individuals they may be prolonged months or more. It is therefore advised that PROZAC should be gradually tapered when discontinuing treatment over a period of at least one to two weeks, according to the patient's needs see Withdrawal symptoms seen on discontinuation of PROZAC, section 4.
Mydriasis Mydriasis has been reported in association with fluoxetine; therefore, caution should be used when prescribing fluoxetine in patients with raised intraocular pressure or those at risk of acute narrow-angle glaucoma.
PROZAC oral solution contains sucrose Patients with rare hereditary problems of fructose intolerance, glucose-galactose malabsorption or sucrase-isomaltase insufficiency should not take this medicine. The long elimination half-lives of both fluoxetine and norfluoxetine should be borne in mind see section 5. Contra-indicated combinations Irreversible, non-selective monoamine oxidase inhibitors e.
Some cases of serious and sometimes fatal reactions have been reported in patients receiving an SSRI in combination with an irreversible, non-selective monoamine oxidase inhibitor MAOI. These cases presented with features resembling serotonin syndrome which may be confounded with [or diagnosed as] neuroleptic malignant syndrome. They will usually improve over one to two weeks.
They will often include more physical complaints, such as nausea or aches and pains. Relapse symptoms gradually develop after two to three weeks. They generally worsen over two to four weeks.
If any symptom continues to last more than a month, consult your doctor. Because Prozac can be prescribed for several different conditions, you should ask your doctor why she has prescribed Prozac for you. In some cases, your doctor may recommend that you stop taking Prozac if she feels that you are no longer at risk for or no longer have chronic or recurrent depression. If your doctor recommends this, it will usually occur after you have taken the medication for at least six to 12 months.
Inform your doctor about any severe, continuing side effects from Prozac. If you have been taking Prozac for longer than eight weeks and do not feel like it is helping with your disorder, explain the symptoms you are continuing to see. This information will help your doctor make an informed decision and decide if the time is right to stop taking Prozac. Depending on how long you have been taking Prozac and its dosage, your doctor may or may not choose to taper your medication.
This means that the drug concentration in your body will not suddenly decrease, and this leads to fewer discontinuation symptoms. If you have been on Prozac for a short period of time, such as six to 12 weeks, or are on a small maintenance dose e. Keep track of your tapering schedule. Write down the date and the dosage you took each day.
Even if you are tapering Prozac, it is still possible to experience discontinuation symptoms, such as those mentioned elsewhere in this article. Talk with your doctor if you develop any discontinuation or other unusual symptoms. No shades — the bright light will help reset your circadian rhythms and can have a positive effect on mood. Go ahead — expose yourself shamelessly.
Make it awkward for the neighbors! Unlike supplements, your skin makes D3 Sulfate, which is a superior form of Vitamin D and has benefits that extend far beyond mood. Vit D supplements are poor substitutes for sunshine. This year I got most of my D from the sun. I take a few Vit D pills in the winter. And finally, this study says combing Prozac with Vitamin D is much better at treating depression than Prozac alone.
Magnesium Magnesium is often called the original chill pill. Magnesium keeps a lid on this. Not enough magnesium and the neurons will eventually die.
Oh, and remember St. Everyone thought it was a natural alternative to Prozac. Too much calcium yes, even from bone health supplements and stress can wipe out magnesium. Food and water is where we used to get most of our magnesium. But processed foods have virtually no magnesium. And they remove magnesium from the tap water to keep pipes clean.
All that calcium and very little magnesium can make you pret-tee tense, anxious and may be even depressed. This study showed rapid recovery from major depression in just 7 days , with magnesium supplementation with each meal and bed time. But the study is a good read and I think you should pay attention to the message.
Leafy green veggies and nuts are good sources of magnesium. Pass on the whole grains — they will spike your glucose, goose your triglycerides, the gluten with mess up our gut and your brain and the phytates will remove valuable nutrients from your body. Unlike Vitamin D3, if you decide to supplement with magnesium, it is very easy to buy the wrong product.
Most drug-store magnesium pills are made of magnesium oxide. Even reputable brands like NatureMade use magnesium oxide. Almost to the point of raging. I have had some irrational thoughts, just negative spiraling thoughts about unrealistic situations.
I have been very nauseous, as well as unable to sleep. Oh, I have woken up with headaches every single day. I'm going to continue working through the withdrawal, as I do not want to go back on lexapro, or any other drug.
I know it will subside eventually. And actually, it has been nice to be able to cry. I will say, that it does make you feel like you are going crazy a bit. My advice, is to expect that you will feel depressed at first, but remember that it will level out.
Jamie at August 7, 4: I've been taking 20mg for three months now and stand 6'5, weigh lbs. When I went to the Dr he increased the dosage it got worse and I just quit the med. Now it is a month later and my left hand is OK but my right hand still doesn't work. I have also noticed people saying they have memory loss from Lexapro. Does that go away? Margi at August 12, 4: I felt fine, I even lost 15 due to exercise and proper eating habits.
I then lost my health insurance and when my Lex ran out I didn't get re-filled because I couldn't afford it. It's been 13 days, the withdrawl has been mild. The brain shocks have been insignificant, other than the brief zap 1 I was a bit moody around day , my libido started to get to back to normal around day I have been exercising daily a vigorous 1 hour bike ride for the past several months and I'm not sure what, if any, impact it had on my usage of Lexapro or my withdrawl.
LTH at August 12, 9: I began taking Lexapro about a year and a half ago because of personal tragedies in my life. I have taken antidepressants before, but usually only for a short period of time, and only to "get through" difficult stages. It helped at first, but then, over time, the side effects pounding heart and anxiety, primarily became more troublesome than my mental state. Well, now I know I would have been better toughing through my difficult time with meditation and yoga. I work in a managerial position, and I've been trying to get off this stuff for about 9 months now.
Every time I taper down the suicidal thoughts, tremors, sweating, tightness in the head, and general irritability make me go back to the original dose. I had a couple of weeks vacation, and was able to taper from 20 mg to 10, and I have tolerated 10 mg okay, but still have tremors, jaw tightness, and major irritability.
Reading these posts help me to know that getting off this stuff is the right thing to do. I am going to go down to 5 mg tonight, and then in a month I am going to stop altogether.
I only hope I can keep my job. Once this drug has you, it is really hard to get off of it. Mandy at August 15, I have only had a few side effects. Weight gain, vivid dreams and memory loss. But I feel good, not as good as I did before I got "sick" it all started with a panic attack that didn't go away. I am happy, no anxiety, no depression, not a panic attack in 6 months. I guess I don't know why everyone else is miserable and I'm not experiencing anything negative.
Part of me is thank full for this drug, I am no longer irritable, and see life more happily. I notice though that I don't have that normal anxiety during situation where i could probably use it. Before going on the drug i was always pretty intense, and emotional, good and bad. NOw, i am more surface and react how i think i "should" act, rather than just feeling and reacting "normally". For example I have been able to sleep with four diferent guys in two weeks and really feel nothing good or bad about it.
Now, that is not the real me, before going on SSRI's i was a virgin, till 21, i valued and respected myself. It really bugged me and I was like , why don't I care about sex, even during sex, I enjoy it to some degree, but rarely orgasm. I tried going off a few times, cold turkey without doctors guidance or tapering I got super depressed, more than i ever remember, and thought about killing myself, I was super negative and irritable.
So i went back on in fear of losing my job. I felt better and more even kealed for sure But still afraid of the irritability to come back. Before chossign to go on meds, I was in therapy for years for depressiona dn anxiety. I started with Paxil and that made me gain weight and feel tired all the time, than prozac for three months, bt that made me impulsive and especially driving I'd take very scary unneccesary risks while driving So on to lexapro.
I tried 15mg of lexapro once or twice, but got angry easily and almos paranoid like thinking people were putting me down, so i went back to 10mg and it went away thank god. It definitly numbs you, in an elusive way. But the sleepign around thing is alarming and out of character I think Any advice would be greatly appreciated, even sharing your stories to see what others are or have gone through.
Any advice about how to prevent going nutso once off Katie at August 22, BOYD at August 23, I had my first full fledged panic attack the day after I took it for the first time. I have never been so scared in my entire life. I woke up terrified to go to class but I made myself go and then I left class to go to the bathroom bc my heart was beating so fast and I was so got I felt like I was going to passs out.
Once in the bathroom I could not leave, even the thought of walking out to get my stuff paralyzed me. It's now day three and my chest hurts from my heart beating so hard and I haven't left my house since that last attack bc I am terrified that it will happen again.
I'm going to call my doctor but does this sound familiar to anyone else? Please I need serious advice on this. I am so scared! Samantha at August 23, BOYD at August 23, 1: After being cleared of any physical aliments, I was diagnosed with depression. I see a therapist and after 6 weeks of therapy decided I needed some help.
After 6 weeks on this dose, I really didn't feel much difference in the depression and motativation. We doubled the dose and I have been taking 20 mg a day for 3 weeks.
I am happier, and back at the gym, no wt gain yet, I am experimenting with when to take the dose because I do experience lathargy. I am trying 10mg in the am and 10mg in the pm. I am not looking forward to coming off of this because of what I have read so far, but for now it is working. I do hate the non-organism part because my husband and I are active sexual, so this has put a damper on things.
Deb at August 23, 6: BOYD at August 24, 2: Burning sensation in chest and back, tremors, heart racing. I'll never take it again! I was in the hospital for 3 days getting tests ran on my heart. I stopped taking the lexapro at that time. Woke me up at 3am out of dead sleep. Have a call in to him now to see whats up. I think I am having an allergic reaction.
Dennis at August 25, After I started, my experience with Lexapro is great. I've had absolutely no negative side effects, none in the beginning, and none now. It calmed me down, I think with a clear head, and I sleep better now than I have in years. The insomnia, nausea, 'flipping out', sex drive decrease, all of that stuff never happened. Also i have a raw, swelling feeling in groin and armpits but lymp nodes are not swollen Has anyone had any of these same symptons? Devin at August 30, I was on 20mg when I began tapering by splitting my dose for about two months, I then saw my Psychiatrist and was told that it could take up to 9 months tapering down.
I told her I wanted to be off of it immediately, but resigned myself to going down a half at a time. I began with 10 mg and took it at around lunchtime. That lasted for about a month when I went down to 5 mgs, boy what a difference in side effects. I had the dizziness and electric shocks when I was on the 10 mgs but it was usually if I forgot to take my dose, and would pretty much go away after I took it.
Before I decreased to the 5mgs I was doing really well and had forgotten my lunchtime dose several times ending up taking it later with no adverse side effects. Since the side effects did not seem to subside when I took the 5mg dose I decided to just go off of it.
That was four days ago Every day I have seen an increase in the dizziness and electric shocks to the point of having the shocks coming with every breath or heartbeat. I was getting a little desperate two nights ago but rode out the storm.
Late afternoon and early evening are the worse for me now, but as far as my mood goes I have been rather even keel, with a little bit of an edge. Through all of this however my clarity and brain function seems to be fine, I am able to concentrate and finish tasks at work. I began medical hypnosis last night with a PsyD who has had success in treating depression.
I will post here as time goes on to let you know how the treatment goes and if I have any lasting side effects from the Lexapro. I feel betrayed by the drug company regarding the safety of Lexapro. I think that it is not the type of drug that can be taken safely for long periods and I think that in a rush to get it to market the long term side effects were not explored.
I believe that the general public has been the collective guinea pig for this medication and I would hope that the FDA would read this board and see that some people are having their lives altered and not in a good way by this medication. When we finally turn to medication for help we do not expect to have our lives turned upside down.
Juliana at September 2, 8: Looking back over this time, I probably seemed more mellow to other people, when in fact I just didn't give a darn. These years seem something of a fog. I spent lots of time playing on my computer, watching TV, and loafing, where before I was an avid cyclist, trim and fit. On Lexapro, I felt dizzy, out of it, unmotivated. But I liked the sexual side effect--I could go for a long time, sometimes it was difficult to ejaculate at all.
I've stopped the Lexapro for about five weeks now. I cut the dosage from 10mg to 5mg daily for five days, then stopped. I feel much better, and actually want to do some work around the house. I feel that tears are close to the surface sometimes I'm not a crier normally , and I am a bit irritable, but that's really just my personality. The sexual effects are troubling. I ejaculate within a minute or two of penetration if it lasts that long.
BobbyT at September 4, 2: While Prozac in many ways gave me back my life, it took away my sex life: I asked my doctor for an alternative and she suggested Lexapro since it did not have the sexual side effects that Prozac had but worked similarly. I gave it a try. In those 3 months, I not only noticed that I was much hungrier than usual I am small and do not generally have a robust appetite , but the other more troubling side effect at least for me is that it caused my face to break out really badly.
I suffer with cystic acne anyway which prior to that had been under somewhat control. The Lexapro brought it over the top. I asked my doctor about it and she said she hadn't read about that in the literature. However, I happened to be speaking to a long distance friend of mine who mentioned she had tried Lexapro but had to go off because it caused havoc to her complexion.
In addition, her friend had a similar experience and wound up going off it. That was enough for me. I went off it too. The side effects alone would cause depression! Deb at September 5, 7: My only question is. Also does it cause terrible sexual side effects or grumpiness? I also feel a bit fatigued but I would rather have this kind of fatigue than drugged feeling.
Chelsey at September 8, 6: I was on 10mg to begin with, but started having panic attack and went up to 20mg. I liked the medication as it seemed to help with my depression and panic attacks.
However, I never had panic attack until I started this medication. I had to recently quit it cold turkey because I found out I was pregnant. This is the 6th day off of it and I can't tell if my nausea is from my morning sickness or withdrawl. Compared to other popular SSRIs, fluoxetine has a strong energizing effect. This makes fluoxetine highly effective in treatment of clinical depression cases where symptoms like depressed mood and lack of energy prevail. This medication can sometimes be prescribed for other uses, but it is strongly recommended that you ask your doctor or pharmacist for more information.
Nevertheless, it is important that you talk to your doctor about the possible risks of using this drug for your particular condition. Dosages in the range of mg per day are standard, with 80 mg considered a maximum. The coating causes the fluoxetine to be dissolved in the intestines instead of the stomach.
Fluoxetine oral liquid comes with a specially marked dropper for measuring the dose if you are not sure how to use the dropper, please ask your pharmacist to show you how to use it. Dilute the liquid in 4 ounces ml of water, apple juice, or Gatorade just before taking it.
Dennis at August 25, And yes, I'm still able to fall asleep at Samantha at August 23, I feel confused mentally today, really foggy feeling, 10mg prozac for anxiety, like there is a cloud in my head. Alcohol Can a person prozac 5 htp and drink alcohol? I went cold turkey off of Paxil with some amazing side bodybuilding accutane online such as looking at someone, turning my head and watching their face kind of faze along. According to the prescribing prozac, all patients 10mg treated with antidepressants, including Prozac, for 10mg indication should be closely monitored and observed for clinical worsening, suicidality and unusual changes in behavior, 10mg prozac for anxiety, especially during the first few months of therapy or during times of dosage adjustments. Too much Prozac can cause a life-threatening condition known as for syndrome. Books and publications 5-HTP: Growth and pubertal development height, 10mg prozac for anxiety, weight, and TANNER staging should therefore be monitored during and after treatment with fluoxetine. I stopped completely last Sunday. Its not something that we can anxiety toss a pill at. This includes aspirin, ibuprofen Advil, Motrinnaproxen Alevecelecoxib Celebrexdiclofenac, indomethacin, meloxicam, and others. Amitriptyline medication Have taken amitriptyline since and sertraline for two weeks — 25 mg. I orginally for drugs to feel normal when i walked down the street instead of kind of paranoid about people looking at me. The challenge will be due somewhat to prescribing habit, but mostly to patient insistence of their preferred medications. Abrupt discontinuation should be avoided.
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