In clinical trials for acute gouty arthritis, etoricoxib was given for 8 days. Postoperative dental surgery pain The recommended dose is 90 mg once daily, limited to a maximum of 3 days. Doses greater than those recommended for each indication have either not demonstrated additional efficacy or have not been studied.
The dose for OA should not exceed 60 mg daily. The dose for RA and ankylosing spondylitis should not exceed 90 mg daily.
The dose for acute gout should not exceed mg daily, limited to a maximum of 8 days treatment. The dose for postoperative acute dental surgery pain should not exceed 90 mg daily, limited to a maximum of 3 days.
Special populations Elderly patients No dosage adjustment is necessary for elderly patients. As with other drugs, caution should be exercised in elderly patients see section 4. Patients with hepatic impairment Regardless of indication, in patients with mild hepatic dysfunction Child-Pugh score a dose of 60 mg once daily should not be exceeded. In patients with moderate hepatic dysfunction Child-Pugh score , regardless of indication, the dose of 30 mg once daily should not be exceeded.
Clinical experience is limited particularly in patients with moderate hepatic dysfunction and caution is advised. Paediatric population Etoricoxib is contra-indicated in children and adolescents under 16 years of age see section 4. This should be considered when rapid symptomatic relief is needed. Caution is advised with treatment of patients most at risk of developing a gastrointestinal complication with NSAIDs; the elderly, patients using any other NSAID or acetylsalicylic acid concomitantly or patients with a prior history of gastrointestinal disease, such as ulceration and GI bleeding.
There is a further increase in the risk of gastrointestinal adverse effects gastrointestinal ulceration or other gastrointestinal complications when etoricoxib is taken concomitantly with acetylsalicylic acid even at low doses.
Cardiovascular effects Clinical trials suggest that the selective COX-2 inhibitor class of drugs may be associated with a risk of thrombotic events especially myocardial infarction MI and stroke , relative to placebo and some NSAIDs.
As the cardiovascular risks of etoricoxib may increase with dose and duration of exposure, the shortest duration possible and the lowest effective daily dose should be used. Patients with significant risk factors for cardiovascular events e. COX-2 selective inhibitors are not a substitute for acetylsalicylic acid for prophylaxis of cardiovascular thrombo-embolic diseases because of their lack of antiplatelet effect.
Therefore antiplatelet therapies should not be discontinued see sections above, 4. Renal effects Renal prostaglandins may play a compensatory role in the maintenance of renal perfusion. Therefore, under conditions of compromised renal perfusion, administration of etoricoxib may cause a reduction in prostaglandin formation and, secondarily, in renal blood flow, and thereby impair renal function.
Patients at greatest risk of this response are those with pre-existing significantly impaired renal function, uncompensated heart failure, or cirrhosis. Monitoring of renal function in such patients should be considered. Fluid retention, oedema and hypertension As with other medicinal products known to inhibit prostaglandin synthesis, fluid retention, oedema and hypertension have been observed in patients taking etoricoxib.
For information regarding a dose related response for etoricoxib see section 5. Caution should be exercised in patients with a history of cardiac failure, left ventricular dysfunction, or hypertension and in patients with pre-existing oedema from any other reason. If there is clinical evidence of deterioration in the condition of these patients, appropriate measures including discontinuation of etoricoxib should be taken.
Etoricoxib may be associated with more frequent and severe hypertension than some other NSAIDs and selective COX-2 inhibitors, particularly at high doses. Therefore, hypertension should be controlled before treatment with etoricoxib see section 4. Blood pressure should be monitored within two weeks after initiation of treatment and periodically thereafter. If blood pressure rises significantly, alternative treatment should be considered.
If signs of hepatic insufficiency occur, or if persistently abnormal liver function tests three times the upper limit of normal are detected, etoricoxib should be discontinued. General If during treatment, patients deteriorate in any of the organ system functions described above, appropriate measures should be taken and discontinuation of etoricoxib therapy should be considered.
Medically appropriate supervision should be maintained when using etoricoxib in the elderly and in patients with renal, hepatic, or cardiac dysfunction. Caution should be used when initiating treatment with etoricoxib in patients with dehydration. Nu depasiti doza de tratament recomandata pentru starea dumneavoastra. Doza recomandata este de 60 mg etoricoxib o data pe zi. Doza recomandata este de 90 mg etoricoxib o data pe zi. Doza recomandata este de mg etoricoxib o data pe zi, doza care trebuie administrata doar in perioada acuta dureroasa.
Administrarea de doze mai mari decat cele recomandate pentru fiecare boala, fie nu a demonstrat eficacitate mai mare, fie nu a fost studiata. Ca urmare, dozele mentionate mai sus sunt dozele maxime recomandate pentru fiecare boala. Daca aveti o boala hepatica usoara, nu trebuie sa luati mai mult de 60 mg etoricoxib pe zi. Daca aveti boala hepatica moderata, nu trebuie sa luati mai mult de 60 mg etoricoxib pe zi, o data la doua zile. Medicul va decide care este doza potrivita pentru dumneavoastra si este important sa luati tratamentul asa cum v-a prescris medicul dumneavoastra.
Daca la vreuna dintre intrebarile de mai jos raspunsul dumneavoastra este "da" si daca nu ati discutat deja despre acest lucru cu medicul dumneavoastra, reveniti la dansul si cereti-i sfatul. S-ar putea ca Arcoxia sa nu fie medicamentul potrivit pentru dumneavoastra sau s-ar putea sa necesitati supraveghere atenta pe tot parcursul tratamentului cu Arcoxia: Arcoxia poate masca sau ascunde febra, care este un semn al infectiei - Intentionati sa deveniti insarcinata?
Acestea pot creste riscul dumneavoastra de boala cardiaca si este necesar sa discutati cu medicul dumneavoastra daca acest medicament vi se potriveste. There are different strengths available for this medicinal product and depending on your disease your doctor will prescribe the tablet strength that is appropriate for you. The recommended dose is: Osteoarthritis The recommended dose is 30 mg once a day, increase to a maximum of 60 mg once a day if needed.
Rheumatoid arthritis The recommended dose is 60 mg once a day, increased to a maximum of 90 mg once a day if needed. Ankylosing spondylitis The recommended dose is 60 mg once a day, increased to a maximum of 90 mg once a day if needed.
Acute pain conditions Etoricoxib should be used only for the acute painful period. Gout The recommended dose is mg once a day which should only be used for the acute painful period, limited to a maximum of 8 days treatment.
Postoperative dental surgery pain The recommended dose is 90 mg once daily, limited to a maximum of 3 days treatment. Etoricoxib may slightly increase your risk of heart attack and stroke and this is why it should not be used in those who have already had heart problems or stroke.
If you think any of these are relevant to you, do not take the tablets until you have consulted your doctor. ARCOXIA can increase blood pressure in some people, especially in high doses, and your doctor will want to check your blood pressure from time to time.
These can increase your risk of heart disease.
The dose 60mg postoperative acute dental surgery pain should not exceed 90 mg daily, limited to a maximum of 3 days. Serious skin reactions, some of them fatal, including exfoliative dermatitis, Stevens-Johnson syndrome, and toxic epidermal necrolysis, have been reported very rarely in association with the use of NSAIDs and some selective COX-2 inhibitors during post-marketing surveillance see section 4. Pret should be discontinued at the first 60mg of skin rash, mucosal lesions, or any other sign of hypersensitivity. This should be considered when rapid symptomatic relief is needed. If you think any of these are relevant to you, do not take the tablets until you have consulted your doctor. Fertility 60mg use of etoricoxib, as with any drug substance known to inhibit COX-2, is not recommended in women attempting to conceive. In clinical trials for acute gouty arthritis, etoricoxib was given for 8 days, arcoxia 60mg pret. Daca deventi insarcinata, intrerupeti tratamentul si informati medicul dumneavoastra. These interactions should arcoxia considered pret patients taking etoricoxib concomitantly with ACE inhibitors or angiotensin II antagonists, arcoxia 60mg pret. Therefore, under arcoxia of compromised renal perfusion, administration of etoricoxib may cause a reduction in prostaglandin formation and, secondarily, in renal blood flow, arcoxia 60mg pret, and thereby impair renal function, arcoxia 60mg pret. In a study in healthy subjects, arcoxia 60mg pret, daily administration of etoricoxib mg did not alter hepatic CYP3A4 activity as assessed by the erythromycin breath test. Medically appropriate supervision should be maintained when using etoricoxib in the elderly and in patients with renal, pret, or cardiac dysfunction. Pharmacokinetic interactions The effect of etoricoxib on the pharmacokinetics of other drugs Lithium: Ca urmare, dozele mentionate mai sus sunt dozele maxime recomandate pentru fiecare boala. There is a further increase in the risk of gastrointestinal adverse effects gastrointestinal ulceration or other gastrointestinal complications when etoricoxib is taken concomitantly with acetylsalicylic acid even arcoxia low doses.
It is different than an pret lightbulb, however, in that it contains a gas called halogen. 60mg poate fi luat cu sau fara alimente. An increase in EE exposure can increase the incidence of adverse tamiflu natco pharma associated with oral contraceptives e. ARCOXIA is indicated in adults and adolescents 16 years of age and older for the arcoxia treatment of moderate pain associated with dental surgery. In some patients with insufficient relief from symptoms, arcoxia 60mg pret, an increased dose of 60 mg once daily may increase efficacy. If there is clinical arcoxia of deterioration in the condition of these patients, appropriate 60mg including discontinuation of etoricoxib should be taken. Possible side effects Like all pret, this medicine can cause side effects, although not everybody gets them. Additional data support a specific association, arcoxia 60mg pret. Daca aveti boala hepatica moderata, nu trebuie sa luati mai mult de 60 mg etoricoxib pe zi, o data la doua zile.
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