This drug may infrequently cause a very serious rarely fatal nervous system disorder neuroleptic malignant syndrome. If you notice any of the following unlikely but very serious side effects, stop taking this medication and seek immediate medical attention: A very serious allergic reaction to this drug is rare.
However, seek immediate medical attention if you notice any of the following symptoms of a serious allergic reaction: This is not a complete list of possible side effects. If you notice other side effects not listed above, contact your doctor or pharmacist. In the US -Call your doctor for medical advice about side effects. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at See also Warning section. This medication should not be used in a person who is unconscious or has severe breathing problems e.
Before taking this medication, tell your doctor or pharmacist if you are allergic to any of its ingredients; or to narcotic pain relievers e. Before using this medication, tell your doctor or pharmacist your medical history, especially of: This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit the use of alcohol and certain other medications that cause drowsiness.
See also Drug Interactions. To reduce dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. This medication may make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths, and sunlamps. Use a sunscreen and wear protective clothing when outdoors. Caution is advised if you have diabetes , alcohol dependence , or liver disease.
Ask your doctor or pharmacist about using this product safely. During pregnancy , this medication should be used only if clearly needed. It is not recommended for use in high doses or for long periods during the last 3 months of pregnancy due to increased risk for serious side effects in a newborn baby e. Tell your doctor immediately if you notice any of these symptoms in your newborn. Discuss the risks and benefits with your doctor.
This product passes into breast milk and may rarely have undesirable effects on a nursing infant. Tell your doctor immediately if your infant develops increased sleepiness, difficulty feeding, or trouble breathing. Discuss the risks and benefits with your doctor before breast-feeding.
Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first. This drug should not be used with the following medications because very serious interactions may occur: If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting this medication.
Tell your doctor or pharmacist if you also take drugs that cause drowsiness such as: Check the labels on all your medicines e. Ask your pharmacist about using those products safely. Also report the use of drugs that might increase seizure risk when combined with this medication such as isoniazid INH , phenothiazines e. Consult your doctor or pharmacist for details.
This medication may interfere with certain laboratory tests e. Make sure laboratory personnel and all your doctors know you use this drug. This document does not contain all possible interactions.
If this medicine is taken by someone else or by accident, get medical help right away. Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets. Do not give to a child younger than 12 years of age. Children between 12 and 18 years of age who are very overweight or have certain other health problems like sleep apnea or other lung or breathing problems must not use promethazine and codeine.
If your child has been given this medicine, ask the doctor for information about the benefits and risks. Some children have had very bad and sometimes deadly breathing problems when using codeine after surgery to remove tonsils or adenoids. Do not give to a child younger than 18 years of age who has had surgery to remove tonsils or adenoids.
Talk with your child's doctor. Uses of Promethazine and Codeine: It is used to relieve coughing. It is used to ease allergy signs. It is used to ease cold signs. If you have an allergy to codeine, promethazine, or any other part of promethazine and codeine. If you are allergic to any drugs like this one, any other drugs, foods, or other substances.
Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs. If you have any of these health problems: Lung or breathing problems like asthma, trouble breathing, or sleep apnea; high levels of carbon dioxide in the blood; or stomach or bowel block or narrowing. If you have taken certain drugs used for low mood depression like isocarboxazid, phenelzine, or tranylcypromine or drugs used for Parkinson's disease like selegiline or rasagiline in the last 14 days.
Taking this medicine within 14 days of those drugs can cause very bad high blood pressure. If you are taking any of these drugs: Linezolid or methylene blue.
Buprenorphine, butorphanol, nalbuphine, or pentazocine. If you are breast-feeding. Do not breast-feed while you take promethazine and codeine. This is not a list of all drugs or health problems that interact with this medicine. Tell your doctor and pharmacist about all of your drugs prescription or OTC, natural products, vitamins and health problems. You must check to make sure that it is safe for you to take promethazine and codeine with all of your drugs and health problems.
Do not start, stop, or change the dose of any drug without checking with your doctor. What are some things I need to know or do while I take Promethazine and Codeine? Tell all of your health care providers that you take this medicine. This includes your doctors, nurses, pharmacists, and dentists. This medicine may be habit-forming with long-term use. Avoid driving and doing other tasks or actions that call for you to be alert until you see how promethazine and codeine affects you.
To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down. Be careful going up and down stairs. This medicine may raise the chance of seizures in some people, including people who have had seizures in the past.
Talk to your doctor to see if you have a greater chance of seizures while taking this medicine. If you have high blood sugar diabetes , you will need to watch your blood sugar closely.
This medicine may cause the results of some pregnancy tests to be wrong. This medicine may affect certain lab tests. Tell all of your health care providers and lab workers that you take promethazine and codeine.
This medicine is not for coughs due to smoking or lung disease. You may get sunburned more easily. Avoid sun, sunlamps, and tanning beds.
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