What does Finax contain? Finax tablets 1mg contain the active ingredient finasteride, which is used to treat male pattern baldness. DHT causes hair follicles in the scalp to gradually shrink producing smaller and thinner hairs, which eventually do not emerge from the follicle.
Finax tablets 1 mg reverse the balding process as it blocks the build-up of DHT in the hair follicles of the scalp, allowing the hair to grow normally. Some of these men continued in additional extension studies receiving finasteride tablets 1 mg, with men entering the fifth year of the study see Figure below.
Hair counts were assessed by photographic enlargements of a representative area of active hair loss. In these two studies in men with vertex baldness, significant increases in hair count were demonstrated at 6 and 12 months in men treated with finasteride tablets 1 mg, while significant hair loss from baseline was demonstrated in those treated with placebo. In men treated with finasteride tablets 1 mg, the maximum improvement in hair count compared to baseline was achieved during the first 2 years.
Although the initial improvement was followed by a slow decline, hair count was maintained above baseline throughout the 5 years of the studies. This increase in hair count was less 56 hairs above original baseline than the increase 91 hairs above original baseline observed after 1 year of treatment in men initially randomized to finasteride tablets 1 mg.
Although the increase in hair count, relative to when therapy was initiated, was comparable between these two groups, a higher absolute hair count was achieved in patients who were started on treatment with finasteride tablets 1 mg in the initial study. This advantage was maintained through the remaining 3 years of the studies. Patient self-assessment was obtained at each clinic visit from a self-administered questionnaire, which included questions on their perception of hair growth, hair loss, and appearance.
This self-assessment demonstrated an increase in amount of hair, a decrease in hair loss, and improvement in appearance in men treated with finasteride tablets 1 mg. Investigator assessment was based on a 7-point scale evaluating increases or decreases in scalp hair at each patient visit. An independent panel rated standardized photographs of the head in a blinded fashion based on increases or decreases in scalp hair using the same 7-point scale as the investigator assessment. Healthcare professionals are asked to report any suspected adverse reactions via the Yellow Card Scheme, at www.
No specific treatment of overdosage with 'Propecia' is recommended. Pharmacological properties Pharmacotherapeutic group: Finasteride has no affinity for the androgen receptor and has no androgenic, anti-androgenic, oestrogenic, anti-oestrogenic, or progestational effects. Inhibition of this enzyme blocks the peripheral conversion of testosterone to the androgen DHT, resulting in significant decreases in serum and tissue DHT concentrations.
Finasteride produces a rapid reduction in serum DHT concentration, reaching significant suppression within 24 hours of dosing. In men with male pattern hair loss, the balding scalp contains miniaturised hair follicles and increased amounts of DHT.
Administration of finasteride decreases scalp and serum DHT concentrations in these men. Finasteride inhibits a process responsible for miniaturisation of the scalp hair follicles, which can lead to reversal of the balding process. A total of 59 cases in the AERS database reported sexual dysfunction that continued for at least three months after Propecia use ended.
On April 11, , the FDA made another revision, explaining that some patients continued to experience libido disorders, ejaculation disorders and orgasm disorders after they stopped taking the drug. The FDA warns that Propecia is not approved for use in women and children.
Women should not handle crushed or broken Propecia tablets when they are pregnant or may potentially be pregnant because of potential risk to a male fetus. DHT is a hormone necessary for normal development of male genitalia. As a result, if a pregnant woman receives finasteride, the drug may cause abnormalities of the external genitalia of a male fetus, according to the FDA. In female rats, low doses of finasteride administered during pregnancy have produced abnormalities of the external genitalia in male offspring, including decreased prostatic and seminal vesicular weights, delayed preputial separation and transient nipple development.
Prostate Cancer The drug also carries a warning that men 55 and older who take Propecia may have an increased risk of an aggressive type of prostate cancer. The warning is based on the dose to treat enlarged prostate, which is five times higher than the dose used for hair loss. In June , the FDA released a safety announcement warning that Propecia and other 5-alpha-reductase inhibitors may increase the risk for high-grade prostate cancer, the deadliest form of prostate cancer.
Men 55 and older who take Propecia may have an increased risk of an aggressive type of prostate cancer High-grade prostate cancer is highly aggressive and grows rapidly, often spreading to other areas like the lymph nodes and bones. Further, high-grade prostate cancer cells are large, difficult to treat and reappear more frequently than low- and intermediate-grade prostate cancers. Although the cancer risk appears to be low, the FDA distributed the announcement to inform doctors and patients of safety revisions to the warning and precaution labels for this class of drugs.
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor right away if any of these unlikely but serious side effects occur: A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at Before taking finasteride, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of:
Finasteride your doctor at once if you notice any breast lumps, finasteride, nipple discharge, or other breast changes. Reporting of suspected adverse reactions Reporting suspected adverse reactions after authorisation of the medicinal product is important. Analysis of PSA data from over patients in PLESS confirmed that in typical patients treated with finasteride 5 mg tablets for six months or more, PSA values should be doubled for comparison with normal ranges in untreated men. In clinical studies for up to 5 years, treatment with finasteride tablets 1 mg slowed the further progression of hair loss observed in the placebo group. Do NOT use Propecia if: If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor. Its structural formula is: This includes any possible side effects not usp in this leaflet, finasteride usp 1mg. Treatment with finasteride 5 mg tablets for 24 weeks to evaluate semen parameters in healthy male volunteers revealed no clinically meaningful effects on sperm concentration, mobility, morphology, or pH, finasteride usp 1mg. Always seek usp advice of your physician usp other qualified health provider with any questions you may have regarding a medical condition. This patent expired in November Tell 1mg doctor or prescriber about all prescription, over-the-counter non-prescriptionand herbal medications that you are taking. The elimination rate of finasteride decreases somewhat with age. When absorbed into 1mg system of a pregnant woman, finasteride may cause abnormalities of the genitals in a male baby. Finasteride your doctor about any unusual or 1mg side effect. Do not take 2 doses at once.
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