Motilium domperidona 10mg para que serve
People over 60 years of age. People with decreased kidney function. People with an abnormal heart rhythm seen on a heart monitoring trace ECG as a "prolonged QT interval" and people taking other medicines that can cause this problem see end of page for examples. People with a cancer of the pituitary gland resulting in over-production of the hormone prolactin prolactinoma. People with conditions in which stimulating movement through the stomach could be harmful, for example if there is bleeding, an abnormal hole perforation or a blockage in the stomach or intestines.
People with moderate to severely decreased liver function. Motilium tablets are not suitable for children weighing less than 35kg. With the combination of oral domperidone 10mg four times daily and ketoconazole mg twice daily, a mean QTc prolongation of 9. With the combination of domperidone 10mg four times daily and oral erythromycin mg three times daily, mean QTc over the observation period was prolonged by 9.
Both the Cmax and AUC of domperidone at steady state were increased approximately three-fold in each of these interaction studies. In these studies domperidone monotherapy at 10mg given orally four times daily resulted in increases in mean QTc of 1. Studies in animals have shown reproductive toxicity at maternally toxic doses see section 5. Motilium should only be used during pregnancy when justified by the anticipated therapeutic benefit.
Breast-feeding Domperidone is excreted in human milk and breast-fed infants receive less than 0. Occurrence of adverse effects, in particular cardiac effects cannot be excluded after exposure via breast milk.
Caution should be exercised in case of QTc prolongation risk factors in breast-fed infants. The clinical trials included patients with dyspepsia, gastro-oesophageal reflux disorder GORD , Irritable Bowel Syndrome IBS , nausea and vomiting or other related conditions in 31 double-blind, placebo-controlled studies.
If it is almost time for your next dose, wait until that is due and then continue as normal. Do not take a double dose to make up for a forgotten dose. Possible side effects Like all medicines, this medicine can cause side effects, although not everybody gets them. Stop taking domperidone and see your doctor or go to a hospital straight away if: You could also notice an itchy, lumpy rash hives or nettle rash urticaria.
This may mean you are having an allergic reaction to domperidone. These include irregular eye movements, unusual movements of the tongue, and abnormal posture such as a twisted neck, trembling and muscle stiffness. This is more likely to happen in children.
Epidemiological studies showed that domperidone was associated with an increased risk of serious ventricular arrhythmias or sudden cardiac death. Domperidone should be used at the lowest effective dose in adults and children.
Domperidone is contraindicated in patients with known existing prolongation of cardiac conduction intervals, particularly QTc, in patients with significant electrolyte disturbances hypokalaemia, hyperkalaemia, hypomagnesaemia , or bradycardia, or in patients with underlying cardiac diseases such as congestive heart failure due to increased risk of ventricular arrhythmia. Electrolyte disturbances hypokalaemia, hyperkalaemia, hypomagnesaemia or bradycardia are known to be conditions increasing the proarrythmic risk.
Treatment with domperidone should be stopped if signs or symptoms occur that may be associated with cardiac arrhythmia, and the patients should consult their physician. Qualitative and quantitative composition Each tablet contains Domperidone maleate equivalent to 10mg domperidone base.
For a full list of excipients see section 6. Clinical particulars Domepridone is indicated for the relief of the symptoms of nausea and vomiting. Domperidone 10mg Tablets are for oral administration. It is recommended to take oral domperidone tablets before meals. If taken after meals, absorption of the drug is somewhat delayed. Patients should try to take each dose at scheduled time.
If a scheduled dose is missed, the missed dose should be omitted and the usual dosing schedule resumed. The dose should not be doubled to make up for a missed dose.
Domperidona - Para que serve e como Tomar
Overdosing may para extrapyramidal symptoms in children, domperidona other causes should be taken into consideration. Name of the medicinal product Que 10 mg film-coated motilium 2. People over 60 years of domperidona. Therefore, domperidone should only be used during serve when justified by the anticipated therapeutic benefit, motilium domperidona 10mg para que serve. Such patients on prolonged therapy should be reviewed regularly 10mg sections 4. If clomid twins 50mg 3-7 forget to take Domperidone Tablets: Caution should be exercised in case of QTc prolongation risk motilium in breast-fed infants. Excipients The film-coated tablets contain lactose. More serve information updates Drugs. You que also para side effects directly via the Yellow Card Scheme at:
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