When we die our body is sent into an open field and cremated, leaving only the white ashes. This is the destination of our body. We cannot take all these possessions along with us after death. They have to be left back. They really do love us but can only feel sad at our demise. Nature has nothing created to make them accompany us after death.
Hence, they can at maximum come to the graveyard to bid us the last goodbye. The things we do in this life may it be good or bad is what is earned by us forever. These are the deeds we take along with us even after our death. We have to pay for the bad deeds performed and will also be rewarded for our good deeds, may it be in the life after death or our next life.
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Non-arteritic anterior ischemic optic neuropathy NAION , a cause of decreased vision including permanent loss of vision, has been reported rarely post-marketing in temporal association with the use of phosphodiesterase type 5 PDE5 inhibitors, including VIAGRA. Most, but not all, of these patients had underlying anatomic or vascular risk factors for developing NAION, including but not necessarily limited to: Alpha-blockers Use caution when co-administering alpha-blockers with VIAGRA because of potential additive blood pressure-lowering effects.
Stronger CYP3A4 inhibitors such as ketoconazole or itraconazole could be expected to have greater effects than seen with saquinavir. Alcohol In a drug-drug interaction study sildenafil 50 mg given with alcohol 0. Therefore, treatments for erectile dysfunction , including VIAGRA, should not be generally used in men for whom sexual activity is inadvisable because of their underlying cardiovascular status.
The evaluation of erectile dysfunction should include a determination of potential underlying causes and the identification of appropriate treatment following a complete medical assessment. VIAGRA has systemic vasodilatory properties that resulted in transient decreases in supine blood pressure in healthy volunteers mean maximum decrease of 8.
While this normally would be expected to be of little consequence in most patients, prior to prescribing VIAGRA, physicians should carefully consider whether their patients with underlying cardiovascular disease could be affected adversely by such vasodilatory effects, especially in combination with sexual activity.
Use with caution in patients with the following underlying conditions which can be particularly sensitive to the actions of vasodilators including VIAGRA — those with left ventricular outflow obstruction e. There are no controlled clinical data on the safety or efficacy of VIAGRA in the following groups; if prescribed, this should be done with caution. Prolonged Erection And Priapism Prolonged erection greater than 4 hours and priapism painful erections greater than 6 hours in duration have been reported infrequently since market approval of VIAGRA.
In the event of an erection that persists longer than 4 hours, the patient should seek immediate medical assistance. If priapism is not treated immediately, penile tissue damage and permanent loss of potency could result.
VIAGRA should be used with caution in patients with anatomical deformation of the penis such as angulation, cavernosal fibrosis or Peyronie's disease , or in patients who have conditions which may predispose them to priapism such as sickle cell anemia , multiple myeloma , or leukemia.
However, there are no controlled clinical data on the safety or efficacy of VIAGRA in patients with sickle cell or related anemias.
Such an event may be a sign of non-arteritic anterior ischemic optic neuropathy NAION , a rare condition and a cause of decreased vision including permanent loss of vision, that has been reported rarely post-marketing in temporal association with the use of all PDE5 inhibitors.
There are no controlled clinical data on the safety or efficacy of VIAGRA in patients with retinitis pigmentosa a minority of these patients have genetic disorders of retinal phosphodiesterases ; if prescribed, this should be done with caution. When vasodilators are used in combination, an additive effect on blood pressure may occur. Consideration should be given to the following: Patients who demonstrate hemodynamic instability on alpha-blocker therapy alone are at increased risk of symptomatic hypotension with concomitant use of PDE5 inhibitors.
Patients should be stable on alpha-blocker therapy prior to initiating a PDE5 inhibitor. In those patients already taking an optimized dose of a PDE5 inhibitor, alpha-blocker therapy should be initiated at the lowest dose.
Stepwise increase in alpha-blocker dose may be associated with further lowering of blood pressure when taking a PDE5 inhibitor.
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