Ivana Addiction Blog 2: While the maximum safe dose is mg tramadol a day, be carefull and look out for overdose symptoms. It can risky if you have no tolerance to tramadol.
So, just in case, you should have the number of the Poison Control Center in mind. Ivana Addiction Blog 6: This is a good question. Both of these medicines can increase the level of serotonin in your body. High serotonin levels may cause changes in body temperature, blood pressure, muscles and behavior, and lead to a Serotonin Syndrome. Contact your healthcare professional e. Tonight I had taking my mg dose at 6p. At 10;30 I went in to take my neurotin and elavil and was talking to my husband while I did this, so was not paying attention and opened and took 2more tramadol.
Do I need to be worried? I have taken this much in a 24 hr period before but only occasionally, but consistently take mg dose daily. At the moment I do not fell any side effects, and attempted to vomit the accidental dose up to no avail. Please advise, thank you marie 1: I have naproxen and hydrocodone can I take this too? Last time I had an attack I only had to take 4 to experience relief.
I almost felt high and went immediately to sleep, and the next day I did not want to get up the whole day. This time no change,no relief, no anything! Ivana Addiction Blog You will be ok. But, you need to get examined by a doctor as soon as possible. How are you feeling now? Please help Gab 7: Call for an over the phone assessment by the Poison Control Center.
Ivana Addiction Blog 4: I have no idea who he got it off because were in school, hes too young to have it on him, but regardless I really care about my friend and I dont want him to die and I have no idea if his parents know Cassandra M 6: I took some yesterday, just mg and got super high. So I waited, took mg more, then I just popped one more 50mg then regretted it.
Am I ok for now? Yesterday it was the itching and euphoria, today a couple of itches and and a headache. I have a pretty high tolerance for opioids and I do this to myself.. Call the Poison Control Center at for an over the phone assessment by a poison expert and to make sure if there is a real concern and what you should do in case you need medical help. I juat cant stop puking Ivana Addiction Blog Can someone drive you to the ER. You may need a saline infusion.
You can Call the Poison Control Center at to talk to a poison expert. The poisn expert will also provide advise on what you should do in case you need medical help. Call the Poison Control Center at for medical advice.
You need a professional assessment and directions on what to do for your son. Tonight I took MG in one shot; I had done the same thing earlier in the day. Usually I get loopy at the 2 to 3 hour mark and then it drops off. I want to come down off what I took today.
I misread the dosage on the info paper and was taking 2 tablets every four hours for three days. That amounts to mg per day. The bottle said to not exceed mg per day. I am concerned as I started to get the cold sweats, nausea, no appetite and am very restless and get VERY little sleep at night and a feeling of despair.
Is that a result of the tramadol. Also is there permanent damage? Will that cause a chemical smell in the nostrils? ANY help you may provide me would be Greatly appreciated as I am very concerned. Thank you for your help and concern, Louis Abdul 9: Please get him to the hospital as soon as possible. He may need to get his stomach pumped and receive medical treatment to prevent organ damage. I got very dizzy and nauseas. Puked all night, 5 days later i still feel kind of weird, but am getting better with each day.
Will I eventually be back to normal or can there be long term permanent effects? Ivana Addiction Blog 5: Effects will eventually subside and you will go back to being normal. But, please never attempt to do anything like that again. Ivana Addiction Blog 1: You should be ok, but seek medical help to prevent major health risks and dangers. Please ask someone to drive you to the hospital or call a taxi. It is horrible and it messes you up.
Yes it did help with the depression a bit, but no better then some of the other ones out there. Worst drug I have ever been on, including my RA drugs. I am not going through that pain again it was to much. Felt like my heart was going to give out". Sam-e is very powerful and builds up in your system as you take it regularly, you need to reduce the dose after a week or so to mg.
ED at December 17, I see an endocrinologist for Hypothroidism and he knows how I cannot tolerate anti-depressants, so he suggested Sam-e. If you take Synthroid.. All of the side effects I have read on the blog are true indications that more research should be done before anyone takes this medicine.. I feel so much better now. I couldn't figure out what was causing my panic attacks.
Jeff at January 11, I start to wander and now after reading this I will never use it again, and someone mention b12, I used before, maybe she is correct, for the ones that is having too much anxiety, I suggest GABA please use small doses and increase until the side effect of same is off or maybe until you change your attitude, Is's scared to think, how about if I don't be the same, I prefer to be slow, no energy etc.. After all I found out I was very happy before this 2 weeks taking same.
If you decide to try or continue taking same, have someone close to you, monitor your reaction, like the lady said, she almost lost her job and in my house, I will loose my family..
I want to tell a little about gaba. Its a amino acid, good to take in moments of anxiety, hot flashes, when eating in excess, too withdraw from sugar, or alcoholl additions. Don't need to use every day. Just in special moments. But don't mixt it with Sr. Jonh;s and others amino acids. Just small dosage in morning or moment of anxiety. I used to be a morning person and I wanted that back without the thought of taking antidepressants. My mood has greatly increased to being a happier girl but, am having headaches and stomach ache after one week.
I'm going to cut back on the dosage and hope the feeling of a stomach flu will go away. Barbara Ann Nigro at January 20, It also covers other treatments for depression and compares them with SAMe, based on controlled studies. They make the point very clear: Otherwise you risk elevated levels of homocysteine, which has many negative effects, including increased risk of heart attack.
Never ever take SAMe alone, without the B-vitamins. Their book also includes a test for depression, used in studies, called the Hamilton Scale. You can evaluate the severity of your own depression. Mine was at 27, about the worst possible, when I first took that test. With mg SAMe, mcg B12, mcg? I got to where I'd score 5 or Mild depression or not depressed at all. I got to experience what it felt like, to not be depressed.
Probably for the first time in my life. It didn't change my personality in some essential way, as I had feared. I felt more resilient, in the face of life's little setbacks.
Instead of like carrying a huge weight on me, all the time. I had more energy than I've ever had. I have experienced the feeling that it was too much energy, or that my depression was replaced with a new problem--anxiety.
Reading this blog I know I'm not alone in that. I've stopped SAMe and everything else because of that, only to go back on it the whole combination when the depression came back, several times. No noticeable withdrawal symptoms except I have known some mental health professionals to get alarmed -- even insist they would not work with me for counseling-- unless I took Rx anti-depressants. I found other professionals to work with.
Quite absurd, someone who's never met me telling me that I'm going to kill myself without drugs, when I know I've been suicidal off and on my whole life and never killed myself, nor even attempted to--and never taken drugs. Some Rx antidepressants have "increased risk of suicide" as a side effect.
Don't passively entrust yourself to professional help--whatever they know, they don't know YOU. I wasn't willing to try pharmaceutical anti-depressants. How could we possibly have deficiencies of chemicals that didn't exist, until some drug company invented them?? The argument for SAMe as antidepressant was more logical--it does exist naturally in the body, and studies do show lower levels, in people who are depressed.
I'm not sure that argument is airtight however. There must be other ways to raise the body's levels of SAMe and lower levels of homocysteine, without taking SAMe -- Brown and Bottiglieri and other writers on natural treatment for depression name some. More fresh vegetables and whole grains, more time outdoors, less emotional stress, meditation, more exercise--directly or indirectly these have the same effects.
The problem is that for people who are depressed, it can be hard to do anything that requires much effort. Unless they are in a situation, where they just have to. So taking supplements can at least help a person get up, to try other things, feel a bit better, get a little momentum going.
I think my optimum might be staying on the vitamins, including the B12 and folic acid, and taking a lower dose of SAMe, maybe or mg. Kelly at January 28, I used to take SAMe every day, and every evening for nearly a year I felt woozy, dizzy and slightly nauseated. It was making me crazy. I still didn't associate the dizziness with them until I started taking the supplements again last week. I felt fine until adding SAMe yesterday to my regimin.
Last night I was so dizzy and nauseated I couldn't keep my dinner down. This morning - I feel almost normal. Wish I had figured this out a year ago Marte at February 20, 1: I went to the doctor yesterday to have me checked for a heart attack and stroke, that's how bad and scared I felt.
However, he did not find any reason for concern and I forgot to even tell him about the Sam-E because I thought it irrelevant. I still didn't think much of that but googled side effect and voila, there it was, most of it anyway.
So I am wondering if there are people who have actually died because of Sam-E and thought it was somethings else. Yes, I know I said the word die, but that is how bad I felt.
I am stopping taking it and will see how I fare. I think any one who thinks they should try it should try it. I took my first two SAM e tablets yesterday and today and I'm feeling very weird, anxious and like my head and limbs are vibrating. Thanks for helping me to find I'm not alone in these side effects. Pat at April 6, I'm afraid that breaking the tablets in halves or quarters will expose some of the potential binders or whatever that may upset your tummies.
Crosby at April 9, 2: If I would have read this Blog a few months ago, I would have never even tried Sam-e. Then I read somewhere on the internet about halving the dose and taking with food They also said to take a break a few days a week.
That's what I do And now I feel energized and lessened depression and can sleep fine, with none of the jittery, heart racing feelings as before.
I also take a Multi- vitamin. It worked for me I am much happier. No flashing ads to try to ignore However, I'm wondering why this blog doesn't show the most recent entries first. I felt like this site was out of date when I saw the first comment was dated March I'm not a blogger I am thinking about starting to take SAMe for reasons related with ongoing mild depression.
I want to just feel like myself again. I have heard alot about side effects, but nothing about whether it is ok to have a few drinks once in a while when on it. This may seem like a silly question but i am just unsure of the risks. I would be really gratefull if anyone can help! Did you notice hair loss when you were taking SAM-e?
I,m losing my hair since i started SAM-e. Riloal at July 15, 8: Please bear with me on this story I have suffered from depr. It was a wonderful thing 4 me. I started with 25mg for a month? She had 2 stop taking it. Y am I talking about Zoloft? I an very upset with the companies making these suplements! It is not the consumer's fault that they are starting with high doses!
I thought it was like a vitamin! I was sooo wrong! I will keep taking it. But a much lower rate! I am also glad of who ever talked about the B12 deficiancy.
That's not my preferance but Your body is trying 2 adapt 2 the SAM-E as it is. But, after awhile when you feel stable, I don't see why you couldn't have a couple of drinks every once in a while.
I myself have 2 b careful with drinking because it tends to make me overindulge in my past trama in a very unproductive way. But I noticed a definet pattern from your blogs that helped me understand what i was getting myself into!
Thot u would apriciate hearing about it. I felt really good for that period of time. I thought, "wow, so this is what an anti-depressant is supposed to do.
All of them made me feel much, much worse in one way or another. After about 3 weeks of taking Sam-e, the side effects kicked in. I first noticed that I was waking up a lot at night and wasn't sleeping well. Then I noticed a lot of short-term memory problems and confusion. I would forget something that someone had just said to me. I felt really ditzy, like I was on drugs. Someone mentioned that this can happen if you don't get enough b, which makes sense, because I wasn't taking a multi or a b complex with this which I can't -that's not an option for me.
I did also feel manic, with increased paranoia and anxiety. All these side effects were too much to handle and I stopped taking it.
I wish those side effects weren't there, because initially I did feel really good and I thought this was going to lift my depression and balance my moods. I wouldn't recommend it. I would try st john's wort, but i take doxycycline for acne and cannot combine the two. Carol at August 3, 6: We both love to drink, probally too much.
Unfortunately, his liver was sending out bad news in the form of some type of enzyme that alerted his insurance company to move him to a more at risk category, so I went looking for a fix, since we really don't want to live a dry life. Within 3 months, his endocrinologist asked him if it was painful to stop drinking. He admitted to not stopping and his Dr. I exercise every day and live a healthy life, am very slender - pounds and have never experienced the negative side effects that are reported by others that have blogged here.
I plan on taking Sam-e to help support my lifestyle and keep me healthy! I was taking Sam-e for about a year at mg everyday. The past couple weeks I started feeling major anxiety and insomnia. I was literally not tired whatsoever despite taking my Sam-e first thing in the morning and I have had 24 hours of no sleep even with a sleep aid. For the past year, my blood pressure has also been elevated despite my exercising regularly and embracing a healthy diet. I stopped taking Sam-e two days ago and am now experiencing similar yet less intense withdrawal symptoms as Zoloft.
I thought I was going crazy. Now I see it's probably the Sam-e causing these problems! Sam-e worked wonders for me in the beginning but now it has caused more harm than good. I suppose that's the way it goes with all medication natural or not. Depression is just something that one has to handle on their own. Lori at August 26, 4: I agree, quality of product matters.
I've been taking it for months, but for joint health, not depression. I take mg of enteric-coated tablets, in the morning 30 min before eating, just as instructions state. I haven't had any of the problems stated here! I have felt a little bloating lately, but is it the SAM-e? I find it interesting that many of the posts here state they're also taking Paxil, Prozac, or some other POTENT drug, yet the posters don't attribute their symptoms to that.
I haven't seen the effects stated by others. MoJo at September 20, 1: It was my first dose. I woke up in the middle of the night with severe nausea and abdominal pain, and very short of breath because my heart was racing so fast-could not count the beats.
I am a cardiac nurse, so no I will not even try a smaller dose. The nausea and abdominal pain continue. As a cardiac nurse, I do not advise anyone with heart palpitations and shortness of breath to continue the Sam-e. It is not for everyone, as any drug or supplement. Traci at September 29, 8: That ultimately causes me to stop using it, but I do recommend it otherwise.
Carik at September 30, 4: These brain zaps are a very weird phenomenon. Reply Link Lacie June 20, , 8: The withdrawal also caused me to twitch, and that stuck around for months. Reply Link Casey July 7, , It feels like it happens multiple times a minute all day and it jolts from my brain to my fingertips. I really hope it stops soon. Reply Link Charlotte May 28, , 3: Any ideas if this is the same thing?
If not, I would consult with a neurologist. Hope you find out what is going on. Reply Link Sean C May 22, , 6: I have been taking Paxil — 30 — 60 mg daily for 4 straight years doctor prescribed 1 or 2 daily as needed — I would only take 2 — 60 mg about once a week.
I have to quit because it has brought my libido to zero. No anxiety what so ever and the few crying spells have been tears of some of the most profound joy I have ever felt I have an extremely strong faith and pray throughout the day for several years now. I feel psychologically terrific but the Brain zaps are horrendous — I can trigger one just by moving my eyes side to side — every time!
I get one about every 10 seconds. Those aside I am so much luckier than others and will pray for all my brothers and sisters enduring this now as well. Hang in there all — Godspeed! Reply Link Tarryn May 20, , 7: I had no idea it was a thing until I read this!
Reply Link Tarryn May 30, , Please please give this a try!!! Reply Link Carole June 12, , 4: I pray it will help me like it has helped you. I am interested in how you came up with this.
Durrell June 14, , 8: What dosage fish oil and B12? Reply Link Tarryn July 2, , And so happy I did so much research! If it helps you, please spread the word to your GP too! Link Tarryn July 2, , Link Cyndi Tustin May 2, , 1: About 18 hours later the extreme fatigue and brain zaps were horrific.
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Heart races, you feel anxious, reducing zoloft 50mg to 25mg, stomach cramps, shortness of breath. I had very strange nightmares and trouble sleeping for 50mg first week or two. At the end of April i started with mg of SAM-e each night. Any thoughts or ideas welcome! Side weight loss with spironolactone and withdrawal symptoms were not mentioned. I have not discerned any noticeable reducing, mine come at all times of the 50mg. Its a amino acid, good to take in moments of anxiety, hot flashes, when eating in excess, too withdraw from sugar, or alcoholl additions. Also, do not split the tablets unless they have a score line and your doctor or pharmacist tells you to do 25mg. For the past year, my blood pressure has also been elevated despite my exercising regularly and embracing a healthy diet. However, brain zapping has just started. That's what I do Brain zaps are ridiculously bad… diarrhea, flu like symptoms… very vivid dreams. I was very moody before I started taking and I don't like taking mood meds, I don't react well with them. I tried switching to a different brand that offered a pill, but it did not work and after a few wells, when the 25mg had completely worn off, I was back zoloft the reducing. Cynthia at September 7, 4: Zoloft felt like this site was out of date when I saw the first comment was dated March
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