In sheer dollars, the drugs remain cheap and the increases appear modest. But because the drugs are used in high volumes, the costs can quickly add up.
Generics account for about eight in every 10 prescriptions filled in the United States. Sign Up Thank you for signing up! Approved, Illicit The risk or severity of adverse effects can be increased when Etidocaine is combined with Amitriptyline. Approved The risk or severity of adverse effects can be increased when Etifoxine is combined with Amitriptyline.
Investigational, Withdrawn The risk or severity of adverse effects can be increased when Etizolam is combined with Amitriptyline. Approved Amitriptyline may decrease the antihypertensive activities of Etomidate. Approved The risk or severity of adverse effects can be increased when Amitriptyline is combined with Etoperidone. Withdrawn The serum concentration of Amitriptyline can be increased when it is combined with Etoposide.
Approved The risk or severity of adverse effects can be increased when Etorphine is combined with Amitriptyline. Illicit, Vet Approved The serum concentration of Amitriptyline can be increased when it is combined with Etravirine. Approved The serum concentration of Everolimus can be increased when it is combined with Amitriptyline.
Approved The serum concentration of Ezetimibe can be increased when it is combined with Amitriptyline. Approved The risk or severity of adverse effects can be increased when Amitriptyline is combined with Ezogabine. Approved The serum concentration of Amitriptyline can be increased when it is combined with Faldaprevir.
Investigational The risk or severity of adverse effects can be increased when Amitriptyline is combined with Felbamate. Approved The serum concentration of Amitriptyline can be increased when it is combined with Felodipine. Approved, Investigational The risk or severity of adverse effects can be increased when Fencamfamine is combined with Amitriptyline.
Approved, Illicit, Withdrawn The risk or severity of adverse effects can be increased when Amitriptyline is combined with Fenoterol. Approved, Investigational The risk or severity of adverse effects can be increased when Amitriptyline is combined with Fentanyl. Approved, Illicit, Investigational, Vet Approved The serum concentration of the active metabolites of Fesoterodine can be increased when Fesoterodine is used in combination with Amitriptyline.
Approved The serum concentration of Fexofenadine can be increased when it is combined with Amitriptyline. Approved The serum concentration of Fidaxomicin can be increased when it is combined with Amitriptyline.
Approved Amitriptyline may increase the QTc-prolonging activities of Flecainide. Approved, Withdrawn The risk or severity of adverse effects can be increased when Amitriptyline is combined with Flibanserin. Approved The metabolism of Amitriptyline can be decreased when combined with Floxuridine. Approved Fluanisone The risk or severity of adverse effects can be increased when Fluanisone is combined with Amitriptyline. Experimental Amitriptyline may increase the QTc-prolonging activities of Fluconazole.
Approved The risk or severity of adverse effects can be increased when Fludiazepam is combined with Amitriptyline. Approved, Illicit Amitriptyline may increase the anticoagulant activities of Fluindione. Investigational The risk or severity of adverse effects can be increased when Amitriptyline is combined with Flunarizine. Approved The risk or severity of adverse effects can be increased when Flunitrazepam is combined with Amitriptyline.
Approved, Illicit The metabolism of Amitriptyline can be decreased when combined with Fluorouracil. Approved The risk or severity of adverse effects can be increased when Fluoxetine is combined with Amitriptyline. Approved, Withdrawn The serum concentration of Amitriptyline can be increased when it is combined with Fluphenazine. Approved The serum concentration of Amitriptyline can be increased when it is combined with Flurazepam. Approved, Illicit The risk or severity of adverse effects can be increased when Fluspirilene is combined with Amitriptyline.
Approved, Investigational The serum concentration of Fluticasone furoate can be increased when it is combined with Amitriptyline. Approved The risk or severity of adverse effects can be increased when Amitriptyline is combined with Fluticasone propionate. Approved The metabolism of Amitriptyline can be decreased when combined with Fluvastatin. Approved The risk or severity of adverse effects can be increased when Fluvoxamine is combined with Amitriptyline. Approved, Investigational The risk or severity of adverse effects can be increased when Amitriptyline is combined with Formoterol.
Approved, Investigational The serum concentration of Amitriptyline can be increased when it is combined with Fosamprenavir. Approved The serum concentration of Amitriptyline can be increased when it is combined with Fosaprepitant.
Approved The serum concentration of Amitriptyline can be increased when it is combined with Fosinopril. Approved The metabolism of Amitriptyline can be increased when combined with Fosphenytoin. Approved The risk or severity of adverse effects can be increased when Fospropofol is combined with Amitriptyline. Approved, Illicit, Investigational The risk or severity of adverse effects can be increased when Amitriptyline is combined with Frovatriptan.
Approved, Investigational Furazolidone may increase the serotonergic activities of Amitriptyline. Approved, Investigational, Vet Approved The serum concentration of Amitriptyline can be increased when it is combined with Fusidic Acid.
Approved The risk or severity of adverse effects can be increased when Gabapentin is combined with Amitriptyline. Approved, Investigational The risk or severity of adverse effects can be increased when Amitriptyline is combined with Gabapentin Enacarbil.
Approved The serum concentration of Amitriptyline can be increased when it is combined with Gabexate. Investigational Amitriptyline may increase the QTc-prolonging activities of Gadobenic acid. Approved The risk or severity of adverse effects can be increased when Gamma Hydroxybutyric Acid is combined with Amitriptyline.
Approved, Illicit, Investigational The serum concentration of Gefitinib can be increased when it is combined with Amitriptyline. Approved, Investigational The serum concentration of Amitriptyline can be increased when it is combined with Geldanamycin.
Experimental, Investigational The serum concentration of Gemcitabine can be increased when it is combined with Amitriptyline. Approved The metabolism of Amitriptyline can be decreased when combined with Gemfibrozil.
Approved Amitriptyline may increase the QTc-prolonging activities of Gemifloxacin. Approved, Investigational The serum concentration of Amitriptyline can be increased when it is combined with Genistein. Investigational Amitriptyline may increase the stimulatory activities of Gepefrine. Experimental The risk or severity of adverse effects can be increased when Gepirone is combined with Amitriptyline. Investigational The serum concentration of Glecaprevir can be increased when it is combined with Amitriptyline.
Approved The risk or severity of adverse effects can be increased when Glutethimide is combined with Amitriptyline. Approved, Illicit The serum concentration of Amitriptyline can be increased when it is combined with Glyburide. Approved The serum concentration of Amitriptyline can be increased when it is combined with Glycerin.
Approved, Investigational The serum concentration of Amitriptyline can be increased when it is combined with GM Experimental Amitriptyline may increase the QTc-prolonging activities of Goserelin.
Approved The serum concentration of Amitriptyline can be increased when it is combined with Gramicidin D.
Approved Amitriptyline may increase the QTc-prolonging activities of Granisetron. Approved, Investigational The serum concentration of Grazoprevir can be increased when it is combined with Amitriptyline.
Approved The serum concentration of Grepafloxacin can be increased when it is combined with Amitriptyline. Investigational, Withdrawn Amitriptyline may decrease the antihypertensive activities of Guanabenz. Approved, Investigational Amitriptyline may decrease the antihypertensive activities of Guanfacine.
Approved, Investigational The risk or severity of adverse effects can be increased when Halazepam is combined with Amitriptyline. Approved The risk or severity of adverse effects can be increased when Halothane is combined with Amitriptyline. Approved, Vet Approved Harmaline may increase the serotonergic activities of Amitriptyline.
Experimental The risk or severity of adverse effects can be increased when Heroin is combined with Amitriptyline. Approved, Illicit, Investigational The metabolism of Amitriptyline can be increased when combined with Hexobarbital. Approved Hydracarbazine may increase the serotonergic activities of Amitriptyline. Experimental Amitriptyline may increase the central nervous system depressant CNS depressant activities of Hydrocodone.
Approved, Illicit The serum concentration of Hydrocortisone can be increased when it is combined with Amitriptyline.
Approved, Vet Approved The risk or severity of adverse effects can be increased when Hydromorphone is combined with Amitriptyline. Approved, Illicit Amitriptyline may increase the stimulatory activities of Hydroxyamphetamine. Approved Hydroxyzine may increase the central nervous system depressant CNS depressant activities of Amitriptyline. Approved The serum concentration of Ibuprofen can be increased when it is combined with Amitriptyline. Approved Amitriptyline may increase the QTc-prolonging activities of Ibutilide.
Approved The serum concentration of Amitriptyline can be increased when it is combined with Idelalisib. Approved The serum concentration of Amitriptyline can be increased when it is combined with Idraparinux.
Investigational Amitriptyline may increase the QTc-prolonging activities of Iloperidone. Approved The metabolism of Amitriptyline can be decreased when combined with Imatinib. Approved The serum concentration of Amitriptyline can be increased when it is combined with Imidapril. Investigational The risk or severity of adverse effects can be increased when Amitriptyline is combined with Imipramine.
Approved The serum concentration of Indacaterol can be increased when it is combined with Amitriptyline. Approved The risk or severity of adverse effects can be increased when Amitriptyline is combined with Indalpine.
Investigational, Withdrawn The metabolism of Amitriptyline can be decreased when combined with Indinavir. Approved The risk or severity of adverse effects can be increased when Indiplon is combined with Amitriptyline. Investigational The serum concentration of Amitriptyline can be increased when it is combined with Indomethacin.
Approved, Investigational The serum concentration of Inotuzumab ozogamicin can be increased when it is combined with Amitriptyline. Approved The therapeutic efficacy of Iobenguane can be decreased when used in combination with Amitriptyline. Approved, Investigational Amitriptyline may increase the stimulatory activities of Iofetamine I Approved Iproclozide may increase the serotonergic activities of Amitriptyline.
Withdrawn Iproniazid may increase the serotonergic activities of Amitriptyline. Withdrawn The metabolism of Amitriptyline can be decreased when combined with Irbesartan. Approved, Investigational The serum concentration of Irinotecan can be increased when it is combined with Amitriptyline.
Approved, Investigational The metabolism of Amitriptyline can be decreased when combined with Isavuconazonium. Approved, Investigational The risk or severity of adverse effects can be increased when Amitriptyline is combined with Isocarboxazid. Approved The risk or severity of adverse effects can be increased when Amitriptyline is combined with Isoetarine.
Approved The risk or severity of adverse effects can be increased when Isoflurane is combined with Amitriptyline. Approved, Vet Approved The serum concentration of Amitriptyline can be increased when it is combined with Isoflurophate. Approved, Investigational, Withdrawn The metabolism of Amitriptyline can be decreased when combined with Isoniazid.
Approved The risk or severity of adverse effects can be increased when Amitriptyline is combined with Isoprenaline. Approved The metabolism of Amitriptyline can be decreased when combined with Isradipine. Approved The metabolism of Amitriptyline can be decreased when combined with Itraconazole.
Approved, Investigational The serum concentration of Amitriptyline can be increased when it is combined with Ivacaftor. Approved The serum concentration of Ivermectin can be increased when it is combined with Amitriptyline.
Approved, Vet Approved The serum concentration of Amitriptyline can be increased when it is combined with Ixazomib. Approved The serum concentration of Amitriptyline can be increased when it is combined with Ketamine.
Approved, Vet Approved The serum concentration of Ketazolam can be increased when it is combined with Amitriptyline. Approved The risk or severity of adverse effects can be increased when Ketobemidone is combined with Amitriptyline. Approved, Investigational The metabolism of Amitriptyline can be decreased when combined with Ketoconazole. Approved, Investigational The serum concentration of Lamivudine can be increased when it is combined with Amitriptyline.
Approved, Investigational The serum concentration of Lamotrigine can be increased when it is combined with Amitriptyline. Approved, Investigational The serum concentration of Amitriptyline can be increased when it is combined with Lansoprazole. Approved, Investigational The serum concentration of Amitriptyline can be increased when it is combined with Lapatinib. Approved, Investigational The serum concentration of Ledipasvir can be increased when it is combined with Amitriptyline.
Approved The metabolism of Amitriptyline can be decreased when combined with Leflunomide. Approved, Investigational The serum concentration of Lenalidomide can be increased when it is combined with Amitriptyline. Approved Amitriptyline may increase the QTc-prolonging activities of Lenvatinib. Approved The serum concentration of Amitriptyline can be increased when it is combined with Lepirudin.
Approved The serum concentration of Amitriptyline can be increased when it is combined with Letaxaban. Investigational Amitriptyline may increase the QTc-prolonging activities of Leuprolide.
Approved, Investigational The serum concentration of Levetiracetam can be increased when it is combined with Amitriptyline. Approved, Investigational The risk or severity of adverse effects can be increased when Levobupivacaine is combined with Amitriptyline. Approved, Investigational The risk or severity of adverse effects can be increased when Amitriptyline is combined with Levocabastine.
Approved The risk or severity of adverse effects can be increased when Amitriptyline is combined with Levocetirizine. Approved The risk or severity of adverse effects can be increased when Amitriptyline is combined with Levodopa. Approved Amitriptyline may increase the QTc-prolonging activities of Levofloxacin. Approved, Investigational The risk or severity of adverse effects can be increased when Levomethadyl Acetate is combined with Amitriptyline. Approved, Investigational The risk or severity of adverse effects can be increased when Amitriptyline is combined with Levomilnacipran.
Approved Amitriptyline may decrease the antihypertensive activities of Levonordefrin. Approved The risk or severity of adverse effects can be increased when Levorphanol is combined with Amitriptyline. Approved The risk or severity of adverse effects can be increased when Amitriptyline is combined with Levosalbutamol. Approved The serum concentration of Amitriptyline can be decreased when it is combined with Levothyroxine.
Approved The serum concentration of Amitriptyline can be increased when it is combined with Lidocaine. Approved, Vet Approved The serum concentration of Amitriptyline can be increased when it is combined with Linagliptin. Approved Linezolid may increase the serotonergic activities of Amitriptyline. Approved, Investigational The serum concentration of Amitriptyline can be decreased when it is combined with Liothyronine. Approved, Vet Approved The serum concentration of Amitriptyline can be decreased when it is combined with Liotrix.
Approved Amitriptyline may increase the stimulatory activities of Lisdexamfetamine. Approved, Investigational The serum concentration of Amitriptyline can be increased when it is combined with Lisinopril.
Approved, Investigational Lithium may increase the neurotoxic activities of Amitriptyline. Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention.
While you are taking this medicine Things you must do Tell your doctor that you are taking this medicine if: Your doctor may occasionally do tests to make sure the medicine is working and to prevent side effects.
Go to your doctor regularly for a check-up. Tell any other doctors, dentists and pharmacists who are treating you that you take this medicine. Amitriptyline may cause dry mouth. Tell your doctor or dentist if your mouth continues to feel dry for more than 2 weeks. Continuing dryness of the mouth may increase the chance of dental disease, including tooth decay and gum disease. Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications.
If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor. It is important to take this medication exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. During pregnancy , this medication should be used only when clearly needed.
Discuss the risks and benefits with your doctor. If you are planning pregnancy, become pregnant , or think you may be pregnant, immediately discuss with your doctor the benefits and risks of using this medication during pregnancy. This medication passes into breast milk and the effect on a nursing infant is unknown. Consult your doctor before breast -feeding.
What should I know regarding pregnancy, nursing and administering Amitriptyline HCL to children or the elderly? Interactions Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions.
Do not start, stop, or change the dosage of any medicines without your doctor's approval. Some products that may interact with this drug include: Taking MAO inhibitors with this medication may cause a serious possibly fatal drug interaction. Avoid taking MAO inhibitors isocarboxazid , linezolid , methylene blue, moclobemide, phenelzine , procarbazine , rasagiline , safinamide, selegiline, tranylcypromine during treatment with this medication. Most MAO inhibitors should also not be taken for two weeks before and after treatment with this medication.
Ask your doctor when to start or stop taking this medication. Other medications can affect the removal of amitriptyline from your body, thereby affecting how amitriptyline works. This is not a complete list. Many drugs besides amitriptyline may affect the heart rhythm QT prolongation in the EKG , including amiodarone , cisapride, dofetilide , pimozide , procainamide , quinidine, sotalol , macrolide antibiotics such as erythromycin , among others.
Therefore, before using amitriptyline, report all medications you are currently using to your doctor or pharmacist. Tell your doctor or pharmacist if you are taking other products that cause drowsiness, including alcohol, marijuana , antihistamines such as cetirizine , diphenhydramine , drugs for sleep or anxiety such as alprazolam , diazepam , zolpidem , muscle relaxants, and narcotic pain relievers such as codeine.
Examples of strong CYP2D6 inhibitors include bupropion, fluoxetine, paroxetine and quinidine. These drugs may produce substantial decreases in TCA metabolism and marked increases in plasma concentrations.
Dose adjustment of amitriptyline may be necessary see section 4. Other Cytochrome P inhibitors: Cimetidine, methylphenidate and calcium-channel blockers e. Antifungals such as fluconazole CYP2C9 inhibitor and terbinafine CYP2D6 inhibitor have been observed to increase serum levels of amitriptyline and nortriptyline. However, fluvoxamine strong CYP1A2 inhibitor was shown to increase amitriptyline plasma concentrations and this combination should be avoided.
Clinically relevant interactions may be expected with concomitant use of amitriptyline and strong CYP3A4 inhibitors such as ketoconazole, itraconazole and ritonavir. Tricyclic antidepressants and neuroleptics mutually inhibit the metabolism of each other; this may lead to a lowered convulsion threshold, and seizures. It may be necessary to adjust the dosage of these drugs. Oral contraceptives, rifampicin, phenytoin, barbiturates, carbamazepine and St. John's Wort Hypericum perforatum may increase the metabolism of tricyclic antidepressants and result in lowered plasma levels of tricyclic antidepressants and reduced antidepressant response.
In the presence of ethanol amitriptyline free plasma concentrations and nortriptyline concentrations were increased. Animal studies have shown reproductive toxicity see section 5. During chronic use and after administration in the final weeks of pregnancy, neonatal withdrawal symptoms can occur. This may include irritability, hypertonia , tremor, irregular breathing, poor drinking and loud crying and possibly anticholinergic symptoms urinary retention, constipation.
Breast-feeding Amitriptyline and its metabolites are excreted into breast milk corresponding to 0. A risk to the suckling child cannot be excluded. Fertility Amitriptyline reduced the pregnancy rate in rats see section 5.
Approved The amitriptyline or severity of adverse effects can be increased when Propofol is combined with Amitriptyline. Approved Minaprine may increase the serotonergic activities of Amitriptyline. Approved, Illicit, Investigational, Vet Approved The serum concentration of the active metabolites of Fesoterodine can be increased when Fesoterodine is used in combination with Amitriptyline. Approved The metabolism of Amitriptyline can be increased when combined with Carbamazepine, amitriptyline teva pharmaceuticals. Experimental The serum concentration of Amitriptyline can be increased when it is combined with Albendazole. Approved Amitriptyline may decrease the antihypertensive activities of Apomorphine. Approved The risk or severity of adverse effects can be increased when Etifoxine is combined with Amitriptyline. Approved, Illicit, Withdrawn The risk or severity of adverse effects can be increased when Amitriptyline is combined with Fenoterol. Do not take a double dose to make up for a forgotten dose. Illicit The serum concentration of Amitriptyline can be increased pharmaceutical it is combined with Batimastat. Approved The serum concentration of Ponatinib can be increased when it is combined with Amitriptyline. Approved, Vet Approved The risk or severity of adverse effects can be teva when Hydromorphone is combined with Amitriptyline. Doses can be increased with 10 mg - 25 mg every 3 — 7 days as tolerated.
Approved The amitriptyline of Amitriptyline can be decreased when combined with Atomoxetine. Approved Hydroxyzine may increase the central nervous system depressant CNS depressant activities of Amitriptyline. It may take up to 4 weeks before your symptoms improve, amitriptyline teva pharmaceuticals. Approved, Investigational The therapeutic efficacy of Moxonidine can be decreased when used in pharmaceutical with Amitriptyline. Approved The risk or severity of adverse effects can be increased when Thiothixene is combined with Amitriptyline. Approved, Vet Approved Amitriptyline may pharmaceutical the anticoagulant activities of Dicoumarol, amitriptyline teva pharmaceuticals. These teva may continue or get worse during the first one to teva months of treatment until the full antidepressant effect of the medicine becomes apparent. Generic drugs, produced after the patents on branded products expire, are cheaper than the original versions and provide a reliable tool for keeping medical spending in check. Experimental Amitriptyline may increase the QTc-prolonging activities of Bedaquiline. Other medicines not listed above may also interact with amitriptyline. Approved Dixyrazine The risk or severity of adverse effects can be increased when Dixyrazine is combined with Amitriptyline, amitriptyline teva pharmaceuticals. Sertraline may cause a loss of blood sugar control increased or decreased blood sugar for some people who have diabetes and glucose tolerance may change. If you are planning pregnancy, become amitriptylineamitriptyline teva pharmaceuticals, or think you may be pregnant, immediately discuss with your doctor the benefits and risks of using this medication during pregnancy.
Duration of treatment Neuropathic pain Treatment is symptomatic and should therefore be continued for an appropriate length of time. Approved, Investigational The risk or severity of adverse effects can be increased when Amitriptyline is combined with Formoterol. Approved, amitriptyline teva pharmaceuticals, Vet Approved The risk or severity of adverse effects can be increased when Dexmethylphenidate is combined with Amitriptyline. Approved The 25mg viagra experiences of Amitriptyline can be increased when teva with Carbamazepine. Approved, amitriptyline teva pharmaceuticals, Investigational The serum concentration of Amitriptyline can amitriptyline increased pharmaceutical it is combined with Genistein. Approved Propanidid The risk or pharmaceutical of adverse effects can be increased when Propanidid is combined with Amitriptyline. Amitriptyline is very similar to nortriptyline. Approved Amitriptyline may decrease the antihypertensive amitriptyline of Ephedra. Illicit The metabolism of Amitriptyline can be decreased pharmaceutical combined amitriptyline Diltiazem. Approved The serum concentration of Teva can be increased when teva is combined with Amitriptyline, amitriptyline teva pharmaceuticals.
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